HitPredict

Interactor 1: GBB2 (P62879)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)
Gene: GNB2

Interactor 2: SEH1 (Q96EE3)
Nucleoporin SEH1 (GATOR2 complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein)
Gene: SEH1L

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005765 - lysosomal membrane GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 360
+	Hs
		921751 GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00		NLE1_HUMAN (210-358): 6.14e-32: 126: 15.58
+	Hs
		282874 GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00		CIAO1_HUMAN (57-321): 2.68e-22: 98: 20.71
+	Hs
		1240442 POC1B_HUMAN (126-340): 2.42e-64: 212: 20.37		POC1A_HUMAN (98-359): 1.13e-51: 178: 13.36
+	Hs
		903349 WDR5B_HUMAN (89-340): 4.94e-82: 253: 25.39		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Sc
		630844 NLE1_YEAST (2-297): 6.96e-77: 246: 19.20		NLE1_YEAST (3-86): 1.94e-16: 82.2: 22.62
+	Hs
		903428 SNR40_HUMAN (130-340): 6.93e-58: 192: 23.36		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Dm
		1358845 WDS_DROME (4-215): 7e-53: 179: 20.18		WDS_DROME (265-360): 3.21e-17: 83.7: 16.67
+	Hs
		1346954 NLE1_HUMAN (2-124): 8.9e-29: 117: 26.77		NLE1_HUMAN (210-358): 6.14e-32: 126: 15.58
+	Hs
		903551 NLE1_HUMAN (2-124): 8.9e-29: 117: 26.77		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Hs
		282843 LIS1_HUMAN (258-340): 1.53e-19: 90.5: 22.89		CIAO1_HUMAN (57-321): 2.68e-22: 98: 20.71
+	Hs
		282871 WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92		CIAO1_HUMAN (57-321): 2.68e-22: 98: 20.71
+	Hs
		792949 LIS1_HUMAN (258-340): 1.53e-19: 90.5: 22.89		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Hs
		903077 WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Mm
		925836 LIS1_MOUSE (258-340): 1.35e-19: 90.8: 22.89		LIS1_MOUSE (272-360): 6.81e-17: 83: 16.85
+	Hs
		792935 LIS1_HUMAN (258-340): 1.53e-19: 90.5: 22.89		LIS1_HUMAN (272-360): 7.69e-17: 83: 16.85
+	Hs
		878165 WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92		SEC13_HUMAN (216-346): 5.58e-17: 82.6: 18.80
+	Sp
		999842 TUP12_SCHPO (142-339): 1.79e-22: 100: 29.27		TUP11_SCHPO (270-359): 5.27e-12: 68.7: 12.90