HitPredict

Interactor 1: ITA8 (P53708)
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]
Gene: ITGA8

Interactor 2: BTNL8 (Q6UX41)
Butyrophilin-like protein 8
Gene: BTNL8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FG-GAP~V-set
Common GO terms	GO:0005886 - plasma membrane GO:0009897 - external side of plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1063 Hs			1 500
+	Hs
		473708 ITA5_HUMAN (36-1063): 0: 1073: 45.16		BTNL3_HUMAN (1-463): 3.63e-120: 362: 73.92
+	Hs
		448077 ITAV_HUMAN (36-1041): 0: 1106: 47.33		BTNL2_HUMAN (2-279): 2.19e-63: 215: 29.64
+	Hs
		654981 ITA6_HUMAN (20-1062): 0: 914: 26.26		BTNL8_HUMAN (17-500): 4.05e-132: 393: 100.00
+	Hs
		1116719 ITA7_HUMAN (1-1060): 0: 913: 27.00		BTNL8_HUMAN (17-500): 4.05e-132: 393: 100.00
+	Hs
		565412 ITA4_HUMAN (12-1062): 0: 898: 24.68		BTNL8_HUMAN (17-500): 4.05e-132: 393: 100.00
+	Hs
		473732 ITA5_HUMAN (36-1063): 0: 1073: 45.16		BTNL2_HUMAN (2-279): 2.19e-63: 215: 29.64
+	Hs
		654982 ITA6_HUMAN (20-1062): 0: 914: 26.26		BTNL3_HUMAN (1-463): 3.63e-120: 362: 73.92
+	Hs
		655024 ITA6_HUMAN (20-1062): 0: 914: 26.26		BTNL2_HUMAN (2-279): 2.19e-63: 215: 29.64
+	Hs
		1116747 ITA7_HUMAN (1-1060): 0: 913: 27.00		BTNL2_HUMAN (2-279): 2.19e-63: 215: 29.64
+	Hs
		603794 ITA2_HUMAN (32-189): 2.46e-32: 138: 24.38		BTNL8_HUMAN (17-500): 4.05e-132: 393: 100.00
+	Hs
		603819 ITA2_HUMAN (32-189): 2.46e-32: 138: 24.38		BTNL2_HUMAN (2-279): 2.19e-63: 215: 29.64