HitPredict

Interactor 1: GNAS2 (P63092)
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Adenylate cyclase-stimulating G alpha protein)
Gene: GNAS

Interactor 2: RIC8B (Q9NVN3)
Synembryn-B (Brain synembryn) (hSyn) (Protein Ric-8B)
Gene: RIC8B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.865

The method score is based on:

Property Details
Experiments 12652642, 28514442, 33961781
Identification Methods pull down, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains G-alpha~Ric8
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 394
Hs

1 520
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024