HitPredict

Interactor 1: XPO2 (P55060)
Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter)
Gene: CSE1L

Interactor 2: RHBT2 (Q9BYZ6)
Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83)
Gene: RHOBTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CAS_CSE1~Ras, Cse1~Ras, IBN_N~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 971 Hs			1 727
+	Hs
		934040 XPO2_HUMAN (1-971): 0: 792: 100.00		CDC42_HUMAN (12-218): 7.12e-92: 286: 36.67
+	Hs
		934052 XPO2_HUMAN (1-971): 0: 792: 100.00		RAC1_HUMAN (12-220): 5.14e-72: 234: 35.38
+	Hs
		934043 XPO2_HUMAN (1-971): 0: 792: 100.00		RHOA_HUMAN (16-216): 1.77e-70: 230: 35.29
+	Hs
		1419430 IPO11_HUMAN (1-966): 1.43e-116: 382: 15.59		RHBT2_HUMAN (1-705): 2.12e-178: 529: 100.00
+	Hs
		189142 IPO8_HUMAN (7-962): 4.27e-163: 507: 18.40		RAC1_HUMAN (12-220): 5.14e-72: 234: 35.38
+	Hs
		227286 IPO7_HUMAN (7-880): 8.55e-159: 496: 19.02		SPOP_HUMAN (305-670): 2.94e-72: 241: 13.30
+	Hs
		334741 IPO7_HUMAN (7-880): 8.55e-159: 496: 19.02		RAC1_HUMAN (12-220): 5.14e-72: 234: 35.38
+	Hs
		955728 IPO11_HUMAN (1-966): 1.43e-116: 382: 15.59		CDC42_HUMAN (12-218): 7.12e-92: 286: 36.67
+	Hs
		955489 IPO9_HUMAN (9-887): 1.79e-110: 368: 14.89		CDC42_HUMAN (12-218): 7.12e-92: 286: 36.67
+	Hs
		988586 TNPO1_HUMAN (2-861): 8.25e-131: 418: 13.34		RAC1_HUMAN (12-220): 5.14e-72: 234: 35.38
+	Hs
		172636 XPO1_HUMAN (7-937): 6.93e-108: 361: 11.85		CDC42_HUMAN (12-218): 7.12e-92: 286: 36.67
+	Hs
		173079 XPO1_HUMAN (7-937): 6.93e-108: 361: 11.85		ABTB2_HUMAN (231-647): 1.53e-77: 270: 17.08
+	Hs
		227564 IMB1_HUMAN (10-789): 6.2e-116: 378: 13.22		SPOP_HUMAN (305-670): 2.94e-72: 241: 13.30
+	Hs
		1015889 IPO11_HUMAN (1-966): 1.43e-116: 382: 15.59		RHOG_HUMAN (12-218): 7.1e-71: 231: 36.19
+	Hs
		962611 IPO11_HUMAN (1-966): 1.43e-116: 382: 15.59		RHOA_HUMAN (16-216): 1.77e-70: 230: 35.29
+	Hs
		988372 IMB1_HUMAN (10-789): 6.2e-116: 378: 13.22		RAC1_HUMAN (12-220): 5.14e-72: 234: 35.38
+	Hs
		1015689 IPO9_HUMAN (9-887): 1.79e-110: 368: 14.89		RHOG_HUMAN (12-218): 7.1e-71: 231: 36.19
+	Hs
		962392 IPO9_HUMAN (9-887): 1.79e-110: 368: 14.89		RHOA_HUMAN (16-216): 1.77e-70: 230: 35.29
+	Hs
		172676 XPO1_HUMAN (7-937): 6.93e-108: 361: 11.85		RAC1_HUMAN (12-220): 5.14e-72: 234: 35.38
+	Hs
		133993 IPO5_HUMAN (90-886): 1.03e-25: 116: 11.41		CDC42_HUMAN (12-218): 7.12e-92: 286: 36.67