HitPredict

Interactor 1: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Interactor 2: SF3A1 (Q15459)
Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114)
Gene: SF3A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.812

Property	Details
Experiments	36736316, 22113938
Identification Methods	affinity chromatography technology, enzymatic study, protein kinase assay
Interaction Type	physical association, direct interaction, phosphorylation reaction

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 793
+	Hs
		1074181 CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47		SF3A1_HUMAN (1-793): 1.4e-107: 349: 100.00
+	Hs
		586769 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		SF3A1_HUMAN (1-793): 1.4e-107: 349: 100.00
+	Hs
		835777 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		SF3A1_HUMAN (1-793): 1.4e-107: 349: 100.00
+	Hs
		625528 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		TITIN_HUMAN (293-702): 3.81e-38: 156: 16.70
+	Hs
		297825 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		K0754_HUMAN (295-761): 2.54e-20: 99.2: 14.29
+	Hs
		554284 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		MUC1_HUMAN (253-757): 1.26e-24: 112: 9.32
+	Hs
		625332 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		RS27A_HUMAN (722-790): 7.14e-21: 92: 30.44
+	Sc
		584735 CSK22_YEAST (2-326): 1.7e-120: 354: 59.51		SEC31_YEAST (158-604): 1.83e-09: 63.7: 8.48
+	Sc
		550035 CSK21_YEAST (1-329): 6.88e-113: 336: 54.32		SEC31_YEAST (158-604): 1.83e-09: 63.7: 8.48