HitPredict

Interactor 1: LAMB2 (P55268)
Laminin subunit beta-2 (Laminin B1s chain) (Laminin-11 subunit beta) (Laminin-14 subunit beta) (Laminin-15 subunit beta) (Laminin-3 subunit beta) (Laminin-4 subunit beta) (Laminin-7 subunit beta) (Laminin-9 subunit beta) (S-laminin subunit beta) (S-LAM beta)
Gene: LAMB2

Interactor 2: VWCE (Q96DN2)
von Willebrand factor C and EGF domain-containing protein (HBV X protein up-regulated gene 11 protein) (HBxAg up-regulated gene 11 protein)
Gene: VWCE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1798 Hs			1 955
+	Hs
		937388 LAMB2_HUMAN (1-1798): 0: 1039: 100.00		FBLN3_HUMAN (46-217): 5.11e-18: 90.3: 25.79
+	Hs
		937395 LAMB2_HUMAN (1-1798): 0: 1039: 100.00		NID2_HUMAN (180-498): 3.22e-16: 86: 18.04
+	Hs
		937387 LAMB2_HUMAN (1-1798): 0: 1039: 100.00		NOTC2_HUMAN (4-384): 2.4e-15: 83.6: 13.10
+	Hs
		937425 LAMB2_HUMAN (1-1798): 0: 1039: 100.00		NELL1_HUMAN (386-746): 9.12e-11: 67.9: 19.77
+	Hs
		462875 LAMB1_HUMAN (17-1797): 0: 1011: 49.83		NID2_HUMAN (180-498): 3.22e-16: 86: 18.04
+	Mm
		384328 LAMB1_MOUSE (17-1797): 0: 1012: 49.89		LAMC1_MOUSE (2-329): 5.82e-10: 65.9: 12.36
+	Hs
		462837 LAMB1_HUMAN (17-1797): 0: 1011: 49.83		LAMC1_HUMAN (59-438): 8.46e-09: 62: 11.43
+	Mm
		107188 F8VQJ3_MOUSE (849-1769): 3.27e-78: 289: 20.57		F8VQJ3_MOUSE (2-329): 1.22e-09: 64.7: 13.22
+	Hs
		572704 LAMC3_HUMAN (894-1774): 2.88e-42: 172: 17.94		NID1_HUMAN (92-351): 1.04e-45: 181: 27.27
+	Mm
		384329 LAMC1_MOUSE (953-1792): 2.4e-36: 153: 15.40		NID1_MOUSE (92-351): 3.89e-41: 166: 25.34
+	Hs
		535812 LAMC1_HUMAN (1009-1798): 7.74e-27: 122: 10.59		NID1_HUMAN (92-351): 1.04e-45: 181: 27.27
+	Dm
		451718 LAMC1_DROME (894-1798): 4.54e-49: 195: 16.34		NOTCH_DROME (403-867): 1.7e-20: 100: 11.56
+	Hs
		857407 NOTC1_HUMAN (169-684): 1.02e-21: 105: 12.52		JAG1_HUMAN (273-873): 6.9e-30: 130: 10.06
+	Hs
		535839 LAMC1_HUMAN (1009-1798): 7.74e-27: 122: 10.59		NID2_HUMAN (180-498): 3.22e-16: 86: 18.04
+	Dm
		95089 NOTCH_DROME (248-656): 6.45e-22: 106: 12.44		E1JHA6_DROME (258-795): 4.94e-21: 102: 12.16
+	Dm
		451712 NOTCH_DROME (248-656): 6.45e-22: 106: 12.44		NOTCH_DROME (403-867): 1.7e-20: 100: 11.56
+	Hs
		535835 LAMC1_HUMAN (1009-1798): 7.74e-27: 122: 10.59		NOTC2_HUMAN (4-384): 2.4e-15: 83.6: 13.10
+	Hs
		857370 NOTC1_HUMAN (169-684): 1.02e-21: 105: 12.52		NOTC1_HUMAN (453-881): 2.53e-19: 96.3: 12.41
+	Hs
		535877 LAMC1_HUMAN (1009-1798): 7.74e-27: 122: 10.59		NELL1_HUMAN (386-746): 9.12e-11: 67.9: 19.77
+	Dm
		451955 NOTCH_DROME (248-656): 6.45e-22: 106: 12.44		Q9W2H2_DROME (371-501): 1.86e-12: 73.3: 23.08