HitPredict

Interactor 1: F1MAL5 (F1MAL5)
Insulin receptor substrate 2
Gene: Irs2

Interactor 2: P85A (Q63787)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: Pik3r1

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 12960006, 19380737
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005158 - insulin receptor binding
GO:0005829 - cytosol
GO:0008286 - insulin receptor signaling pathway
GO:0019901 - protein kinase binding
GO:0019903 - protein phosphatase binding
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1327
Rn

1 724
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024