HitPredict

Interactor 1: CCL20 (P78556)
C-C motif chemokine 20 (Beta-chemokine exodus-1) (CC chemokine LARC) (Liver and activation-regulated chemokine) (Macrophage inflammatory protein 3 alpha) (MIP-3-alpha) (Small-inducible cytokine A20) [Cleaved into: CCL20(1-67); CCL20(1-64); CCL20(2-70)]
Gene: CCL20

Interactor 2: CXL17 (Q6UXB2)
C-X-C motif chemokine 17 (6-Cys CXCL17) (Dendritic cell and monocyte chemokine-like protein) (DMC) (VEGF coregulated chemokine 1) [Cleaved into: 4-Cys CXCL17]
Gene: CXCL17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28381538
Identification Methods	pull down, filter binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 96 Hs			1 119
+	Hs
		945620 CCL8_HUMAN (20-96): 1.12e-28: 100: 28.57		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		528221 CCL2_HUMAN (20-95): 7.22e-25: 91.2: 26.32		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		1166407 CCL13_HUMAN (20-96): 1.43e-24: 90.5: 22.08		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		528267 CCL5_HUMAN (19-92): 6.49e-24: 88.5: 28.21		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		815515 XCL1_HUMAN (6-95): 1.53e-22: 85.5: 29.03		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		1166409 XCL2_HUMAN (6-95): 6.59e-22: 83.9: 29.03		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		134308 CCL21_HUMAN (23-92): 1.76e-21: 83.5: 31.94		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		1166410 CCL26_HUMAN (29-94): 1.43e-20: 80.1: 25.76		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		1166406 CCL17_HUMAN (8-90): 2.22e-14: 64.3: 24.10		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		179467 CCL25_HUMAN (7-94): 6.29e-13: 62: 25.00		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00