HitPredict

Interactor 1: MTPN (P58546)
Myotrophin (Protein V-1)
Gene: MTPN

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	11971907
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ank_2~RHD_dimer
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 118 Hs			1 551
+	Hs
		1045692 BARD1_HUMAN (31-118): 2.61e-31: 118: 27.27		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		1045780 EHMT1_HUMAN (6-78): 4.41e-18: 80.3: 26.03		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		171229 MYPT1_HUMAN (4-87): 2.12e-16: 75.5: 25.00		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		1045916 ANR26_HUMAN (2-66): 3.68e-16: 74.9: 23.08		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		295492 PSD10_HUMAN (64-118): 5.74e-15: 69.5: 21.82		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		1045484 ANKH1_HUMAN (2-93): 1.33e-10: 58.9: 35.87		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		946403 MTPN_HUMAN (1-118): 3.18e-42: 136: 100.00		REL_HUMAN (12-523): 3.58e-165: 484: 41.64
+	Hs
		626138 MTPN_HUMAN (1-118): 3.18e-42: 136: 100.00		NFKB1_HUMAN (7-451): 2.24e-153: 465: 29.51
+	Hs
		626343 BARD1_HUMAN (31-118): 2.61e-31: 118: 27.27		NFKB1_HUMAN (7-451): 2.24e-153: 465: 29.51
+	Hs
		295454 PSD10_HUMAN (64-118): 5.74e-15: 69.5: 21.82		NFKB1_HUMAN (7-451): 2.24e-153: 465: 29.51
+	Hs
		626281 ANKH1_HUMAN (2-93): 1.33e-10: 58.9: 35.87		NFKB1_HUMAN (7-451): 2.24e-153: 465: 29.51
+	Hs
		177224 ANR28_HUMAN (12-93): 8.48e-09: 53.5: 34.15		NFAC4_HUMAN (5-461): 5.81e-101: 326: 17.82