HitPredict

Interactor 1: PP4C (P60510)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X)
Gene: PPP4C

Interactor 2: 2A5G (Q13362)
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-gamma) (PP2A B subunit isoform PR61-gamma) (PP2A B subunit isoform R5-gamma) (Renal carcinoma antigen NY-REN-29)
Gene: PPP2R5C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	B56~Metallophos
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 307 Hs			1 524
+	Hs
		977480 PP2AB_HUMAN (6-307): 0: 525: 65.23		2A5G_HUMAN (1-524): 0: 898: 100.00
+	Hs
		994207 PP2AA_HUMAN (6-307): 0: 524: 65.89		2A5G_HUMAN (1-524): 0: 898: 100.00
+	Hs
		786587 PP1G_HUMAN (1-304): 0: 519: 43.81		2A5G_HUMAN (1-524): 0: 898: 100.00
+	Hs
		967705 PP1A_HUMAN (2-304): 0: 517: 43.89		2A5G_HUMAN (1-524): 0: 898: 100.00
+	Hs
		951976 PP4C_HUMAN (1-307): 0: 537: 100.00		2A5D_HUMAN (23-523): 0: 821: 80.52
+	Mm
		977644 PP2AB_MOUSE (6-307): 0: 525: 65.23		Q91V89_MOUSE (17-523): 0: 825: 80.35
+	Mm
		994023 PP2AA_MOUSE (6-307): 0: 524: 65.89		Q91V89_MOUSE (17-523): 0: 825: 80.35
+	Hs
		977492 PP2AB_HUMAN (6-307): 0: 525: 65.23		2A5D_HUMAN (23-523): 0: 821: 80.52
+	Hs
		96931 PP2AA_HUMAN (6-307): 0: 524: 65.89		E9PFR3_HUMAN (23-523): 0: 821: 80.52
+	Hs
		994222 PP2AA_HUMAN (6-307): 0: 524: 65.89		2A5D_HUMAN (23-523): 0: 821: 80.52
+	Hs
		967731 PP1A_HUMAN (2-304): 0: 517: 43.89		2A5D_HUMAN (23-523): 0: 821: 80.52
+	Dm
		661969 PP2A_DROME (2-307): 0: 524: 64.05		Q9VEC6_DROME (25-488): 0: 764: 70.08
+	Dm
		661961 PP2A_DROME (2-307): 0: 524: 64.05		Q9VB23_DROME (22-438): 0: 690: 72.01
+	Hs
		977504 PP2AB_HUMAN (6-307): 0: 525: 65.23		2A5E_HUMAN (21-436): 0: 673: 72.12
+	Hs
		994236 PP2AA_HUMAN (6-307): 0: 524: 65.89		2A5E_HUMAN (21-436): 0: 673: 72.12
+	Hs
		977496 PP2AB_HUMAN (6-307): 0: 525: 65.23		2A5A_HUMAN (23-417): 0: 668: 72.15
+	Hs
		994228 PP2AA_HUMAN (6-307): 0: 524: 65.89		2A5A_HUMAN (23-417): 0: 668: 72.15
+	Hs
		967761 PP1A_HUMAN (2-304): 0: 517: 43.89		2A5E_HUMAN (21-436): 0: 673: 72.12
+	Hs
		977497 PP2AB_HUMAN (6-307): 0: 525: 65.23		2A5B_HUMAN (18-436): 0: 662: 68.50
+	Hs
		994229 PP2AA_HUMAN (6-307): 0: 524: 65.89		2A5B_HUMAN (18-436): 0: 662: 68.50