HitPredict

Interactor 1: UB2G2 (P60604)
Ubiquitin-conjugating enzyme E2 G2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G2) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2)
Gene: UBE2G2

Interactor 2: BIRC8 (Q96P09)
Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis)
Gene: BIRC8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	19690564
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 165 Hs			1 236
+	Hs
		1399328 UB2D4_HUMAN (4-164): 1.27e-73: 218: 36.03		BIRC8_HUMAN (1-236): 1.71e-86: 257: 100.00
+	Hs
		982291 UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03		BIRC8_HUMAN (1-236): 1.71e-86: 257: 100.00
+	Hs
		982277 UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03		BIRC7_HUMAN (1-236): 7.02e-61: 194: 33.47
+	Hs
		982273 UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03		MIB2_HUMAN (37-234): 1.21e-28: 115: 19.34
+	At
		762751 UBC8_ARATH (4-164): 1.43e-72: 216: 36.03		RGLG3_ARATH (53-234): 4.97e-24: 100: 15.61
+	At
		762748 UBC8_ARATH (4-164): 1.43e-72: 216: 36.03		LUL3_ARATH (86-233): 1.32e-23: 99.3: 17.76
+	Hs
		982264 UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03		RFFL_HUMAN (64-236): 5.99e-24: 100: 17.78
+	Hs
		982269 UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03		RNF34_HUMAN (161-236): 2.92e-23: 98: 36.84
+	Hs
		1361437 UB2D4_HUMAN (4-164): 1.27e-73: 218: 36.03		MYLIP_HUMAN (166-235): 7.55e-21: 92.2: 35.71
+	Hs
		982263 UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03		MYLIP_HUMAN (166-235): 7.55e-21: 92.2: 35.71
+	Hs
		906657 UB2D1_HUMAN (4-164): 2.21e-72: 215: 36.03		BIRC3_HUMAN (4-158): 6.1e-18: 84.3: 24.20
+	Hs
		982180 UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03		BIRC3_HUMAN (4-158): 6.1e-18: 84.3: 24.20
+	Hs
		906658 UB2D1_HUMAN (4-164): 2.21e-72: 215: 36.03		BIRC2_HUMAN (4-148): 3.09e-16: 79.3: 24.49
+	Hs
		982181 UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03		BIRC2_HUMAN (4-148): 3.09e-16: 79.3: 24.49
+	Hs
		1022814 UB2D4_HUMAN (4-164): 1.27e-73: 218: 36.03		XIAP_HUMAN (3-211): 1.27e-13: 71.6: 15.07
+	Hs
		906644 UB2D1_HUMAN (4-164): 2.21e-72: 215: 36.03		XIAP_HUMAN (3-211): 1.27e-13: 71.6: 15.07
+	Hs
		982166 UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03		XIAP_HUMAN (3-211): 1.27e-13: 71.6: 15.07
+	Hs
		1295603 UB2D4_HUMAN (4-164): 1.27e-73: 218: 36.03		MIB1_HUMAN (158-233): 9.22e-12: 66: 25.00
+	Hs
		906699 UB2D1_HUMAN (4-164): 2.21e-72: 215: 36.03		MIB1_HUMAN (158-233): 9.22e-12: 66: 25.00
+	Hs
		982235 UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03		MIB1_HUMAN (158-233): 9.22e-12: 66: 25.00