HitPredict

Interactor 1: CDC42 (P60766)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: RBCC1 (Q9ESK9)
RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (FAK family kinase-interacting protein of 200 kDa) (FIP200) (LaXp180)
Gene: Rb1cc1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35670107
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Mm			1 1588
+	Mm
		988914 RAC1_MOUSE (1-191): 1.15e-81: 242: 70.31		RBCC1_MOUSE (1-1588): 6.45e-139: 470: 100.00
+	Hs
		773156 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		MYH10_HUMAN (104-1174): 1.54e-46: 186: 11.40
+	Hs
		772724 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		MYH9_HUMAN (839-1587): 1.46e-36: 153: 11.84
+	Hs
		601313 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		GRDN_HUMAN (100-850): 1.26e-28: 128: 9.21
+	Hs
		772743 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		MYH9_HUMAN (839-1587): 1.46e-36: 153: 11.84
+	Hs
		1191484 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		GRDN_HUMAN (100-850): 1.26e-28: 128: 9.21
+	Mm
		878598 RAC1_MOUSE (1-191): 1.15e-81: 242: 70.31		CTRO_MOUSE (853-1529): 2.95e-30: 133: 12.45
+	Mm
		878597 CDC42_MOUSE (1-191): 9.95e-80: 237: 100.00		CTRO_MOUSE (853-1529): 2.95e-30: 133: 12.45
+	Hs
		988410 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		GRDN_HUMAN (100-850): 1.26e-28: 128: 9.21
+	Hs
		601518 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		MRCKB_HUMAN (1135-1487): 3.07e-15: 83.8: 15.03
+	Hs
		157213 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		CTRO_HUMAN (941-1520): 1.85e-22: 107: 11.80
+	Hs
		601393 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		MY18A_HUMAN (610-1088): 6.24e-15: 82.9: 12.53
+	Hs
		1433601 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		MRCKB_HUMAN (1135-1487): 3.07e-15: 83.8: 15.03
+	Hs
		601383 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		DLG5_HUMAN (955-1281): 5.25e-09: 63.5: 24.65
+	Hs
		988378 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		EEA1_HUMAN (219-979): 1.85e-15: 84.5: 11.56
+	Hs
		988860 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		MRCKB_HUMAN (1135-1487): 3.07e-15: 83.8: 15.03
+	Hs
		988578 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		MY18A_HUMAN (610-1088): 6.24e-15: 82.9: 12.53
+	Hs
		1351390 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		DLG5_HUMAN (955-1281): 5.25e-09: 63.5: 24.65
+	Hs
		720983 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		CLIP1_HUMAN (993-1510): 1.39e-10: 68.7: 11.81
+	Hs
		988547 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		DLG5_HUMAN (955-1281): 5.25e-09: 63.5: 24.65