HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31478661
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 2725
+	Hs
		637455 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		FLNA_HUMAN (147-2725): 0: 1228: 35.27
+	Hs
		278059 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		FLNB_HUMAN (146-2725): 0: 1196: 35.23
+	Hs
		601243 RHOQ_HUMAN (4-187): 7.38e-91: 266: 67.94		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		1028873 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		988286 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		1015372 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		955068 CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		955390 CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00		SYNE1_HUMAN (33-344): 6.38e-100: 364: 28.65
+	Hs
		961961 RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		580995 RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		466207 RHOC_HUMAN (5-191): 3.38e-76: 228: 52.41		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		953397 RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		1028802 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		389259 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		FINC_HUMAN (1545-2724): 4.55e-64: 246: 13.76
+	Ce
		145082 RAC1_CAEEL (1-191): 1.28e-82: 244: 65.97		UNC89_CAEEL (312-2706): 6.3e-36: 153: 10.22
+	Ce
		110130 G5EBV3_CAEEL (2-191): 2.73e-79: 236: 58.95		UNC89_CAEEL (312-2706): 6.3e-36: 153: 10.22
+	Ce
		145083 CDC42_CAEEL (1-191): 2.47e-77: 231: 86.39		UNC89_CAEEL (312-2706): 6.3e-36: 153: 10.22