HitPredict

Interactor 1: SYP22 (P93654)
Syntaxin-22 (AtSYP22) (AtVAM3) (Protein SHOOT GRAVITROPISM 3)
Gene: SYP22

Interactor 2: VTI11 (Q9SEL6)
Vesicle transport v-SNARE 11 (AtVTI11) (Protein SHOOT GRAVITROPISM 4) (Vesicle soluble NSF attachment protein receptor VTI1a) (AtVTI1a) (Vesicle transport v-SNARE protein VTI1a)
Gene: VTI11

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.855

Property	Details
Experiments	24556609, 10557242, 12815100
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~V-SNARE_C
Common GO terms	GO:0000149 - SNARE binding GO:0000325 - plant-type vacuole GO:0005484 - SNAP receptor activity GO:0005773 - vacuole GO:0006906 - vesicle fusion and 1 others more... GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 268 At			1 221
+	At
		955689 SYP22_ARATH (1-256): 6.24e-70: 218: 100.00		VTI12_ARATH (1-220): 5.51e-66: 204: 60.63
+	At
		1352079 SYP42_ARATH (2-266): 3.49e-57: 187: 19.10		VTI12_ARATH (1-220): 5.51e-66: 204: 60.63
+	At
		249589 SYP41_ARATH (4-266): 5.12e-56: 184: 20.97		VTI12_ARATH (1-220): 5.51e-66: 204: 60.63
+	Mm
		292714 Q8BH40_MOUSE (14-266): 8.59e-65: 204: 29.25		VTI1A_MOUSE (1-217): 4e-58: 184: 32.72
+	At
		249590 SYP41_ARATH (4-266): 5.12e-56: 184: 20.97		VTI11_ARATH (1-221): 1.42e-64: 201: 100.00
+	At
		1107361 SYP21_ARATH (1-256): 5.47e-56: 182: 58.05		VTI11_ARATH (1-221): 1.42e-64: 201: 100.00
+	Mm
		1206468 Q8BH40_MOUSE (14-266): 8.59e-65: 204: 29.25		Q91XH6_MOUSE (2-221): 1.59e-54: 175: 27.23
+	Hs
		151576 STX1A_HUMAN (17-266): 2.61e-61: 196: 18.61		GOSR2_HUMAN (5-217): 1.31e-57: 183: 13.62
+	Mm
		250839 STX7_MOUSE (14-266): 3.39e-63: 200: 29.25		VTI1B_MOUSE (2-221): 1.17e-54: 176: 27.23
+	Hs
		151600 STX12_HUMAN (1-254): 2.47e-59: 191: 24.51		GOSR2_HUMAN (5-217): 1.31e-57: 183: 13.62
+	Hs
		1205352 STX12_HUMAN (1-254): 2.47e-59: 191: 24.51		VTI1A_HUMAN (1-221): 2.1e-55: 177: 32.13
+	Hs
		151531 STX7_HUMAN (14-266): 4.5e-57: 185: 29.25		GOSR2_HUMAN (5-217): 1.31e-57: 183: 13.62
+	Ce
		183452 STX1A_CAEEL (4-266): 1.23e-61: 197: 17.78		GOSR2_CAEEL (5-216): 4.52e-52: 169: 17.81
+	Dm
		1098107 STX1A_DROME (8-268): 2.13e-60: 194: 17.10		GOSR2_DROME (5-217): 7.02e-53: 171: 16.74
+	Hs
		178716 STX7_HUMAN (14-266): 4.5e-57: 185: 29.25		VTI1A_HUMAN (1-221): 2.1e-55: 177: 32.13
+	Dm
		1098112 STX1A_DROME (8-268): 2.13e-60: 194: 17.10		Q9W0N6_DROME (3-220): 4.54e-51: 166: 28.18
+	Hs
		1084006 STX1A_HUMAN (17-266): 2.61e-61: 196: 18.61		VTI1B_HUMAN (2-221): 1.25e-47: 158: 27.23
+	Hs
		699289 STX2_HUMAN (4-266): 3.61e-60: 194: 17.71		VTI1B_HUMAN (2-221): 1.25e-47: 158: 27.23
+	Hs
		1205392 STX12_HUMAN (1-254): 2.47e-59: 191: 24.51		VTI1B_HUMAN (2-221): 1.25e-47: 158: 27.23
+	Hs
		178840 STX7_HUMAN (14-266): 4.5e-57: 185: 29.25		VTI1B_HUMAN (2-221): 1.25e-47: 158: 27.23