HitPredict

Interactor 1: ACTZ (P61163)
Alpha-centractin (Centractin) (ARP1) (Actin-RPV) (Centrosome-associated actin homolog)
Gene: ACTR1A

Interactor 2: NINL (Q9Y2I6)
Ninein-like protein
Gene: NINL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	28718761, 26485645
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~EF-hand_7
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 376 Hs			1 1382
+	Hs
		837269 ACTY_HUMAN (1-376): 0: 728: 90.43		NINL_HUMAN (1-1382): 1.12e-100: 354: 100.00
+	Hs
		958443 ACTZ_HUMAN (1-376): 0: 771: 100.00		PLEC_HUMAN (141-1132): 2.84e-25: 117: 10.73
+	Hs
		958469 ACTZ_HUMAN (1-376): 0: 771: 100.00		NIN_HUMAN (693-1358): 6e-17: 89.2: 8.94
+	Hs
		953067 ACTB_HUMAN (7-376): 0: 581: 52.41		CP250_HUMAN (421-1382): 5.49e-33: 141: 9.52
+	Hs
		952834 ACTB_HUMAN (7-376): 0: 581: 52.41		PLEC_HUMAN (141-1132): 2.84e-25: 117: 10.73
+	Hs
		993183 ACTG_HUMAN (7-376): 0: 581: 52.67		PLEC_HUMAN (141-1132): 2.84e-25: 117: 10.73
+	Hs
		977703 ACTA_HUMAN (5-376): 0: 576: 52.66		PLEC_HUMAN (141-1132): 2.84e-25: 117: 10.73
+	Hs
		995607 ACTC_HUMAN (5-376): 0: 576: 52.93		PLEC_HUMAN (141-1132): 2.84e-25: 117: 10.73
+	Hs
		996459 ACTS_HUMAN (5-376): 0: 576: 52.39		PLEC_HUMAN (141-1132): 2.84e-25: 117: 10.73
+	Rn
		953311 ACTB_RAT (7-376): 0: 581: 52.41		MYH10_RAT (740-1377): 4.22e-21: 103: 11.32
+	Hs
		773154 ACTC_HUMAN (5-376): 0: 576: 52.93		MYH10_HUMAN (697-1382): 1.3e-21: 104: 11.99
+	Mm
		977876 ACTA_MOUSE (5-376): 0: 576: 52.66		MYH6_MOUSE (195-1079): 2.89e-21: 103: 10.56
+	Hs
		773153 ACTH_HUMAN (7-376): 0: 573: 52.94		MYH10_HUMAN (697-1382): 1.3e-21: 104: 11.99
+	Rn
		953303 ACTB_RAT (7-376): 0: 581: 52.41		MYH9_RAT (937-1382): 2.72e-16: 87.3: 8.57
+	Mm
		953280 ACTB_MOUSE (7-376): 0: 581: 52.41		MYH9_MOUSE (937-1382): 3.45e-16: 86.9: 8.13
+	Mm
		993452 ACTH_MOUSE (7-376): 0: 573: 52.94		PLEC_MOUSE (65-1045): 2.61e-18: 93.9: 10.59
+	Hs
		772705 ACTB_HUMAN (7-376): 0: 581: 52.41		MYH9_HUMAN (37-554): 3.89e-11: 70.3: 9.27
+	Hs
		772729 ACTG_HUMAN (7-376): 0: 581: 52.67		MYH9_HUMAN (37-554): 3.89e-11: 70.3: 9.27
+	Hs
		772733 ACTC_HUMAN (5-376): 0: 576: 52.93		MYH9_HUMAN (37-554): 3.89e-11: 70.3: 9.27
+	Hs
		772734 ACTS_HUMAN (5-376): 0: 576: 52.39		MYH9_HUMAN (37-554): 3.89e-11: 70.3: 9.27