HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: MTUS2 (Q5JR59)
Microtubule-associated tumor suppressor candidate 2 (Cardiac zipper protein) (Microtubule plus-end tracking protein TIP150) (Tracking protein of 150 kDa)
Gene: MTUS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1369
+	Hs
		157168 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		CTRO_HUMAN (613-1336): 3.23e-30: 133: 9.79
+	Hs
		157213 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		CTRO_HUMAN (613-1336): 3.23e-30: 133: 9.79
+	Hs
		156856 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		CTRO_HUMAN (613-1336): 3.23e-30: 133: 9.79
+	Hs
		962019 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		ROCK1_HUMAN (816-1333): 8.21e-28: 124: 11.90
+	Hs
		988339 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		ROCK1_HUMAN (816-1333): 8.21e-28: 124: 11.90
+	Hs
		466240 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		ROCK1_HUMAN (816-1333): 8.21e-28: 124: 11.90
+	Hs
		773156 RHOG_HUMAN (1-193): 1.49e-76: 229: 54.40		MYH10_HUMAN (928-1347): 4.54e-17: 89.6: 16.17
+	Rn
		97301 RHOA_RAT (1-193): 2.21e-80: 238: 99.48		CTRO_RAT (895-1290): 4.87e-14: 80: 13.40
+	Mm
		878608 RHOA_MOUSE (1-193): 2.21e-80: 238: 99.48		CTRO_MOUSE (895-1290): 7.43e-14: 79.2: 13.40
+	Hs
		772724 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		MYH9_HUMAN (724-1205): 5.3e-14: 79.5: 8.62
+	Mm
		878598 RAC1_MOUSE (1-193): 7e-79: 235: 57.22		CTRO_MOUSE (895-1290): 7.43e-14: 79.2: 13.40
+	Hs
		962148 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		MRCKA_HUMAN (703-1094): 4.15e-13: 76.8: 6.41
+	Hs
		988432 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		MRCKA_HUMAN (703-1094): 4.15e-13: 76.8: 6.41
+	Hs
		772743 RHOG_HUMAN (1-193): 1.49e-76: 229: 54.40		MYH9_HUMAN (724-1205): 5.3e-14: 79.5: 8.62
+	Hs
		962678 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		MRCKB_HUMAN (1181-1369): 2.4e-10: 67.6: 10.35
+	Hs
		988860 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		MRCKB_HUMAN (1181-1369): 2.4e-10: 67.6: 10.35
+	Hs
		270791 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		ROCK2_HUMAN (1201-1369): 2.51e-09: 64.1: 14.54
+	Hs
		270795 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		ROCK2_HUMAN (1201-1369): 2.51e-09: 64.1: 14.54
+	Hs
		270757 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		ROCK2_HUMAN (1201-1369): 2.51e-09: 64.1: 14.54
+	Hs
		270800 RHOG_HUMAN (1-193): 1.49e-76: 229: 54.40		ROCK2_HUMAN (1201-1369): 2.51e-09: 64.1: 14.54