HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: SDK1 (Q7Z5N4)
Protein sidekick-1
Gene: SDK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 2213
+	Hs
		978122 RHOB_HUMAN (1-191): 9.8e-73: 219: 83.94		SDK1_HUMAN (1-2213): 0: 1440: 100.00
+	Hs
		978055 RHOB_HUMAN (1-191): 9.8e-73: 219: 83.94		SDK2_HUMAN (1-1578): 2.64e-162: 556: 20.54
+	Hs
		962011 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		PTPRS_HUMAN (89-1139): 5.01e-69: 261: 15.32
+	Hs
		988333 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		PTPRS_HUMAN (89-1139): 5.01e-69: 261: 15.32
+	Hs
		466235 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		PTPRS_HUMAN (89-1139): 5.01e-69: 261: 15.32
+	Hs
		955122 CDC42_HUMAN (1-193): 4.17e-76: 228: 52.33		PTPRS_HUMAN (89-1139): 5.01e-69: 261: 15.32
+	Hs
		953423 RAC3_HUMAN (1-179): 3.87e-73: 220: 57.54		PTPRS_HUMAN (89-1139): 5.01e-69: 261: 15.32
+	Hs
		977977 RHOB_HUMAN (1-191): 9.8e-73: 219: 83.94		PTPRS_HUMAN (89-1139): 5.01e-69: 261: 15.32
+	Hs
		522635 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		PTPRF_HUMAN (5-1014): 6.68e-57: 221: 15.81
+	Hs
		522641 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		PTPRF_HUMAN (5-1014): 6.68e-57: 221: 15.81
+	Hs
		466080 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		PTPRF_HUMAN (5-1014): 6.68e-57: 221: 15.81
+	Hs
		522650 RHOG_HUMAN (1-193): 1.49e-76: 229: 54.40		PTPRF_HUMAN (5-1014): 6.68e-57: 221: 15.81
+	Hs
		522632 CDC42_HUMAN (1-193): 4.17e-76: 228: 52.33		PTPRF_HUMAN (5-1014): 6.68e-57: 221: 15.81
+	Hs
		522584 RAC2_HUMAN (1-193): 2.82e-75: 226: 53.61		PTPRF_HUMAN (5-1014): 6.68e-57: 221: 15.81
+	Hs
		522631 RAC3_HUMAN (1-179): 3.87e-73: 220: 57.54		PTPRF_HUMAN (5-1014): 6.68e-57: 221: 15.81
+	Hs
		522639 RHOB_HUMAN (1-191): 9.8e-73: 219: 83.94		PTPRF_HUMAN (5-1014): 6.68e-57: 221: 15.81
+	Ce
		145082 RAC1_CAEEL (1-193): 1.28e-79: 236: 55.44		UNC89_CAEEL (188-396): 9.39e-09: 63.2: 13.83
+	Ce
		110130 G5EBV3_CAEEL (2-193): 4.38e-77: 230: 50.52		UNC89_CAEEL (188-396): 9.39e-09: 63.2: 13.83
+	Ce
		145089 RHO1_CAEEL (1-192): 1.52e-74: 224: 85.94		UNC89_CAEEL (188-396): 9.39e-09: 63.2: 13.83
+	Ce
		145083 CDC42_CAEEL (1-193): 2.05e-73: 221: 50.78		UNC89_CAEEL (188-396): 9.39e-09: 63.2: 13.83