HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: DAAM2 (Q86T65)
Disheveled-associated activator of morphogenesis 2
Gene: DAAM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Drf_FH3~Ras, Drf_GBD~Ras
Common GO terms	GO:0030036 - actin cytoskeleton organization GO:0032956 - regulation of actin cytoskeleton organization GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1068
+	Hs
		962668 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		DAAM1_HUMAN (1-1068): 0: 864: 65.68
+	Hs
		988853 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		DAAM1_HUMAN (1-1068): 0: 864: 65.68
+	Hs
		962540 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		DIAP3_HUMAN (18-1066): 0: 720: 24.37
+	Hs
		988751 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		DIAP3_HUMAN (18-1066): 0: 720: 24.37
+	Hs
		962396 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		FMNL2_HUMAN (19-1046): 0: 685: 20.54
+	Hs
		988622 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		FMNL2_HUMAN (19-1046): 0: 685: 20.54
+	Hs
		337573 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		FMNL1_HUMAN (42-1046): 0: 632: 22.29
+	Hs
		337577 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		FMNL1_HUMAN (42-1046): 0: 632: 22.29
+	Hs
		962240 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		FMNL3_HUMAN (19-1046): 0: 603: 22.27
+	Hs
		988862 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		FHOD1_HUMAN (71-1061): 3.95e-170: 532: 17.20
+	Hs
		962103 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		INF2_HUMAN (568-1062): 3.09e-105: 359: 25.45
+	Hs
		988403 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		INF2_HUMAN (568-1062): 3.09e-105: 359: 25.45
+	Hs
		962564 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		FMN2_HUMAN (553-1012): 7.75e-100: 349: 23.52
+	Hs
		988766 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		FMN2_HUMAN (553-1012): 7.75e-100: 349: 23.52
+	Hs
		252434 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		DIAP1_HUMAN (26-597): 3.04e-98: 340: 21.43
+	Hs
		252441 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		DIAP1_HUMAN (26-597): 3.04e-98: 340: 21.43
+	Hs
		258555 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		DIAP2_HUMAN (35-489): 1.26e-98: 338: 22.15
+	Sc
		448546 RHO1_YEAST (3-188): 1.51e-97: 283: 73.12		BNI1_YEAST (580-1068): 7.41e-81: 292: 21.08
+	Hs
		258558 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		DIAP2_HUMAN (35-489): 1.26e-98: 338: 22.15
+	Hs
		252406 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		DIAP1_HUMAN (26-597): 3.04e-98: 340: 21.43