HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: KBRS2 (Q9NYR9)
NF-kappa-B inhibitor-interacting Ras-like protein 2 (I-kappa-B-interacting Ras-like protein 2) (Kappa B-Ras protein 2) (KappaB-Ras2)
Gene: NKIRAS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 191
+	Hs
		959311 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		RAP1B_HUMAN (3-189): 1.32e-82: 244: 26.60
+	Hs
		959316 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		RAP1B_HUMAN (3-189): 1.32e-82: 244: 26.60
+	Hs
		988585 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		RIT1_HUMAN (1-189): 8.06e-80: 238: 23.28
+	Hs
		955905 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		RAB8A_HUMAN (1-187): 2.01e-78: 234: 23.04
+	Hs
		955911 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		RAB8A_HUMAN (1-187): 2.01e-78: 234: 23.04
+	Hs
		539791 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		RALA_HUMAN (6-176): 1.39e-76: 229: 26.32
+	Hs
		466179 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		RAB8A_HUMAN (1-187): 2.01e-78: 234: 23.04
+	Hs
		466084 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		RALA_HUMAN (6-176): 1.39e-76: 229: 26.32
+	Hs
		961930 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		RAB1A_HUMAN (5-185): 3.58e-71: 216: 22.65
+	Hs
		956235 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		RAB2A_HUMAN (5-185): 5.65e-71: 215: 19.89
+	Hs
		962463 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		RAB1B_HUMAN (5-184): 1.71e-70: 214: 21.67
+	Hs
		981255 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		RAB1A_HUMAN (5-185): 3.58e-71: 216: 22.65
+	Hs
		956241 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		RAB2A_HUMAN (5-185): 5.65e-71: 215: 19.89
+	Hs
		962088 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		RB11B_HUMAN (5-178): 1.25e-69: 212: 24.14
+	Hs
		988691 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		RAB1B_HUMAN (5-184): 1.71e-70: 214: 21.67
+	Hs
		957903 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		RAB14_HUMAN (5-185): 4.17e-69: 211: 20.44
+	Hs
		988393 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		RB11B_HUMAN (5-178): 1.25e-69: 212: 24.14
+	Hs
		466181 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		RAB2A_HUMAN (5-185): 5.65e-71: 215: 19.89
+	Hs
		976191 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		RB11A_HUMAN (5-183): 3.58e-69: 211: 24.02
+	Mm
		312772 RAC1_MOUSE (1-193): 7e-79: 235: 57.22		RAD_MOUSE (6-152): 3.94e-11: 62.4: 31.29