Interactor 1: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Interactor 2: PIM3 (Q86V86)
Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)
Gene: PIM3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 19166854
Identification Methods protein kinase assay
Interaction Type phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0043066 - negative regulation of apoptotic process
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 491
Hs

1 326
+ Hs
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024