HitPredict

Interactor 1: STXB1 (P61764)
Syntaxin-binding protein 1 (MUNC18-1) (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67)
Gene: STXBP1

Interactor 2: DDR1 (Q08345)
Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)
Gene: DDR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 594 Hs			1 913
+	Hs
		411685 STXB1_HUMAN (1-594): 0: 680: 100.00		NTRK1_HUMAN (607-902): 1.44e-66: 240: 45.27
+	At
		1300027 KEULE_ARATH (4-590): 9.18e-177: 517: 26.69		CRK10_ARATH (594-911): 2.15e-116: 372: 21.65
+	Hs
		541614 SCFD1_HUMAN (4-588): 8.05e-163: 481: 14.62		FGFR1_HUMAN (540-905): 4.74e-109: 357: 32.52
+	Hs
		648607 SCFD1_HUMAN (4-588): 8.05e-163: 481: 14.62		FGFR4_HUMAN (554-910): 1.49e-107: 352: 33.87
+	Hs
		125701 STXB3_HUMAN (1-593): 0: 584: 50.59		NTRK1_HUMAN (607-902): 1.44e-66: 240: 45.27
+	Hs
		179624 SCFD1_HUMAN (4-588): 8.05e-163: 481: 14.62		MUSK_HUMAN (593-906): 7.41e-103: 341: 36.99
+	Hs
		541705 VPS45_HUMAN (12-582): 5.05e-154: 456: 17.81		FGFR1_HUMAN (540-905): 4.74e-109: 357: 32.52
+	Hs
		648695 VPS45_HUMAN (12-582): 5.05e-154: 456: 17.81		FGFR4_HUMAN (554-910): 1.49e-107: 352: 33.87
+	Rn
		580580 Q99PV2_RAT (1-593): 0: 583: 50.59		INSR_RAT (600-908): 1.99e-51: 198: 36.25
+	Hs
		1157011 SCFD1_HUMAN (4-588): 8.05e-163: 481: 14.62		NTRK3_HUMAN (607-905): 4.08e-67: 242: 43.63
+	Hs
		412325 SCFD1_HUMAN (4-588): 8.05e-163: 481: 14.62		NTRK1_HUMAN (607-902): 1.44e-66: 240: 45.27
+	Hs
		412669 VPS45_HUMAN (12-582): 5.05e-154: 456: 17.81		NTRK1_HUMAN (607-902): 1.44e-66: 240: 45.27
+	Hs
		439801 SCFD1_HUMAN (4-588): 8.05e-163: 481: 14.62		INSR_HUMAN (600-908): 7.74e-53: 202: 37.42
+	Hs
		477247 SCFD1_HUMAN (4-588): 8.05e-163: 481: 14.62		ROS1_HUMAN (571-902): 5.23e-52: 201: 35.38
+	Hs
		465587 SCFD1_HUMAN (4-588): 8.05e-163: 481: 14.62		IGF1R_HUMAN (600-908): 4.53e-51: 197: 37.22
+	Hs
		1034303 SCFD1_HUMAN (4-588): 8.05e-163: 481: 14.62		ROR2_HUMAN (608-905): 1.58e-50: 194: 38.26
+	Rn
		148088 VPS45_RAT (12-582): 1.24e-155: 460: 17.98		INSR_RAT (600-908): 1.99e-51: 198: 36.25
+	Hs
		465665 VPS45_HUMAN (12-582): 5.05e-154: 456: 17.81		IGF1R_HUMAN (600-908): 4.53e-51: 197: 37.22
+	Hs
		412406 VP33A_HUMAN (6-584): 2.97e-136: 411: 16.09		NTRK1_HUMAN (607-902): 1.44e-66: 240: 45.27
+	Hs
		412589 VP33B_HUMAN (6-585): 3.47e-115: 357: 13.83		NTRK1_HUMAN (607-902): 1.44e-66: 240: 45.27