HitPredict

Interactor 1: LMO4 (P61968)
LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)
Gene: LMO4

Interactor 2: SSBP2 (P81877)
Single-stranded DNA-binding protein 2 (Sequence-specific single-stranded-DNA-binding protein 2)
Gene: SSBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	24981860, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 165 Hs			1 361
+	Hs
		1010758 LHX8_HUMAN (23-158): 3.97e-48: 160: 39.71		SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00
+	Mm
		965536 LMO4_MOUSE (1-165): 8.51e-43: 141: 100.00		SSBP2_MOUSE (1-361): 8.32e-60: 198: 99.72
+	Hs
		1229372 LHX8_HUMAN (23-158): 3.97e-48: 160: 39.71		SSBP4_HUMAN (1-361): 2.17e-51: 177: 68.73
+	Hs
		1229373 LHX8_HUMAN (23-158): 3.97e-48: 160: 39.71		SSBP3_HUMAN (5-361): 4.08e-51: 176: 74.16
+	Hs
		1010763 LMO3_HUMAN (13-152): 6.28e-41: 136: 47.86		SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00
+	Mm
		1297636 LMO3_MOUSE (13-152): 6.28e-41: 136: 47.86		SSBP2_MOUSE (1-361): 8.32e-60: 198: 99.72
+	Hs
		961475 ISL1_HUMAN (22-162): 8.36e-39: 136: 36.55		SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00
+	Mm
		961501 ISL1_MOUSE (22-162): 8.36e-39: 136: 36.55		SSBP2_MOUSE (1-361): 8.32e-60: 198: 99.72
+	Hs
		681787 RBTN2_HUMAN (23-140): 7.71e-36: 123: 46.61		SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00
+	Hs
		965506 LMO4_HUMAN (1-165): 8.51e-43: 141: 100.00		SSBP4_HUMAN (1-361): 2.17e-51: 177: 68.73
+	Hs
		965507 LMO4_HUMAN (1-165): 8.51e-43: 141: 100.00		SSBP3_HUMAN (5-361): 4.08e-51: 176: 74.16
+	Hs
		1347375 LMO3_HUMAN (13-152): 6.28e-41: 136: 47.86		SSBP4_HUMAN (1-361): 2.17e-51: 177: 68.73
+	Hs
		961490 ISL1_HUMAN (22-162): 8.36e-39: 136: 36.55		SSBP4_HUMAN (1-361): 2.17e-51: 177: 68.73
+	Hs
		1347376 LMO3_HUMAN (13-152): 6.28e-41: 136: 47.86		SSBP3_HUMAN (5-361): 4.08e-51: 176: 74.16
+	Hs
		961491 ISL1_HUMAN (22-162): 8.36e-39: 136: 36.55		SSBP3_HUMAN (5-361): 4.08e-51: 176: 74.16
+	Mm
		961502 ISL1_MOUSE (22-162): 8.36e-39: 136: 36.55		SSBP3_MOUSE (5-361): 4.08e-51: 176: 74.16
+	Dm
		1305679 Q8IQX7_DROME (19-162): 2.03e-37: 133: 47.22		Q9VEB9_DROME (5-333): 1.75e-31: 125: 38.73
+	Hs
		319090 LMO4_HUMAN (1-165): 8.51e-43: 141: 100.00		SC24D_HUMAN (85-286): 1.32e-26: 113: 17.73
+	Dm
		305323 O77284_DROME (19-162): 5.96e-36: 128: 47.22		Q9VEB9_DROME (5-333): 1.75e-31: 125: 38.73
+	Ce
		113370 G5EFL5_CAEEL (15-165): 2.23e-34: 129: 18.79		CO4A1_CAEEL (79-356): 6.15e-21: 96.6: 18.79