Protein: SSBP2
Single-stranded DNA-binding protein 2 (Sequence-specific single-stranded-DNA-binding protein 2)

Gene: SSBP2
Organism: Homo sapiens
Interactions: 123
UniProt ID: P81877

Gene Ontology (top 5):
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006355 - regulation of DNA-templated transcription
GO:0045944 - positive regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1010761

LDB1
LIM domain-binding protein 1

7

13

Small-scale

0.749

High

1010776

SSBP3
Single-stranded DNA-binding protein 3

6

16

High-throughput

0.732

High

1010767

LHX4
LIM/homeobox protein Lhx4

5

20

High-throughput

0.714

High

1010768

ISL2
Insulin gene enhancer protein ISL-2

5

20

High-throughput

0.712

High

1010775

SSBP4
Single-stranded DNA-binding protein 4

5

14

High-throughput

0.712

High

1010792

LHX6
LIM/homeobox protein Lhx6

4

20

High-throughput

0.699

High

961475

ISL1
Insulin gene enhancer protein ISL-1

4

20

High-throughput

0.694

High

965432

LMO4
LIM domain transcription factor LMO4

4

20

High-throughput

0.694

High

253011

LMX1B
LIM homeobox transcription factor 1-beta

3

20

High-throughput

0.667

High

605189

TAL1
T-cell acute lymphocytic leukemia protein 1

3

3

Small-scale

0.667

High

681787

RBTN2
Rhombotin-2

3

20

Small-scale

0.667

High

1010777

IDI2
Isopentenyl-diphosphate delta-isomerase 2

3

2

High-throughput

0.667

High

1010788

I36RA
Interleukin-36 receptor antagonist protein

2

4

High-throughput

0.633

High

174235

ARHGA
Rho guanine nucleotide exchange factor 10

2

3

High-throughput

0.611

High

1010759

RHG22
Rho GTPase-activating protein 22

2

0

High-throughput

0.602

High

1010757

INT3
Integrator complex subunit 3

2

0

Small-scale

0.559

High

1010745

CDK6
Cyclin-dependent kinase 6

1

2

Small-scale

0.550

High

1010746

EWS
RNA-binding protein EWS

1

18

High-throughput

0.541

High

248690

PEPL
Periplakin

1

5

High-throughput

0.536

High

277641

H2AY
Core histone macro-H2A.1

1

2

High-throughput

0.536

High

289251

SPB7
Serpin B7

1

5

High-throughput

0.536

High

424496

PAI2
Plasminogen activator inhibitor 2

1

5

High-throughput

0.536

High

457853

INVO
Involucrin

1

2

High-throughput

0.536

High

502312

H2A1
Histone H2A type 1

1

1

High-throughput

0.536

High

568138

PLSL
Plastin-2

1

4

High-throughput

0.536

High

595393

H15
Histone H1.5

1

3

High-throughput

0.536

High

682020

RBTN1
Rhombotin-1

1

20

High-throughput

0.536

High

713360

SPB3
Serpin B3

1

5

High-throughput

0.536

High

827741

STAT3
Signal transducer and activator of transcription 3

1

1

High-throughput

0.536

High

868670

LEG7
Galectin-7

1

3

High-throughput

0.536

High

1010760

S1A7A
Protein S100-A7A

1

1

High-throughput

0.536

High

1010763

LMO3
LIM domain only protein 3

1

20

High-throughput

0.536

High

1010764

NDRG1
Protein NDRG1

1

1

High-throughput

0.536

High

1010782

PICK1
PRKCA-binding protein

1

2

High-throughput

0.536

High

1010787

CALL5
Calmodulin-like protein 5

1

1

High-throughput

0.536

High

1010789

LHX3
LIM/homeobox protein Lhx3

1

20

High-throughput

0.536

High

1010790

ASC
Apoptosis-associated speck-like protein containing a CARD

1

1

High-throughput

0.536

High

1010791

NDRG2
Protein NDRG2

1

1

High-throughput

0.536

High

1010793

TRI33
E3 ubiquitin-protein ligase TRIM33

1

6

Small-scale

0.536

High

1010794

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

1

High-throughput

0.536

High

1010797

PYGO1
Pygopus homolog 1

1

8

High-throughput

0.536

High

256462

TOM1
Target of Myb1 membrane trafficking protein

1

0

High-throughput

0.518

High

126232

ST2B1
Sulfotransferase 2B1

1

0

High-throughput

0.513

High

474613

VIME
Vimentin

1

0

High-throughput

0.513

High

483897

HMOX1
Heme oxygenase 1

1

0

High-throughput

0.513

High

578652

GLNA
Glutamine synthetase

1

0

High-throughput

0.513

High

692681

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.513

High

1010774

TREX2
Three prime repair exonuclease 2

1

0

High-throughput

0.513

High

223929

LDB2
LIM domain-binding protein 2

1

13

Small-scale

0.508

High

1010752

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

3

High-throughput

0.508

High

85972

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

7

High-throughput

0.489

High

369339

A1AT
Alpha-1-antitrypsin

1

6

High-throughput

0.489

High

380279

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

3

High-throughput

0.489

High

380624

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

2

High-throughput

0.489

High

387817

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

4

High-throughput

0.489

High

409570

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

3

High-throughput

0.489

High

592831

CBR1
Carbonyl reductase [NADPH] 1

1

1

High-throughput

0.489

High

615211

IL1RA
Interleukin-1 receptor antagonist protein

1

4

High-throughput

0.489

High

874772

SPB4
Serpin B4

1

5

High-throughput

0.489

High

935713

MFAP4
Microfibril-associated glycoprotein 4

1

4

High-throughput

0.489

High

1010766

EVPL
Envoplakin

1

5

High-throughput

0.489

High

1010772

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

3

High-throughput

0.489

High

1010786

IL36G
Interleukin-36 gamma

1

4

High-throughput

0.489

High

1010750

DLG1
Disks large homolog 1

1

0

High-throughput

0.480

High

138990

BCL9
B-cell CLL/lymphoma 9 protein

1

8

High-throughput

0.479

High

142935

NFIB
Nuclear factor 1 B-type

1

10

High-throughput

0.479

High

181498

TBXT
T-box transcription factor T

1

2

High-throughput

0.479

High

270238

MTG16
Protein CBFA2T3

1

2

Small-scale

0.479

High

473912

NFIC
Nuclear factor 1 C-type

1

11

High-throughput

0.479

High

519940

ANDR
Androgen receptor

1

3

High-throughput

0.479

High

538385

EGR2
E3 SUMO-protein ligase EGR2

1

2

High-throughput

0.479

High

547128

PYC
Pyruvate carboxylase, mitochondrial

1

2

Small-scale

0.479

High

662401

GATA2
Endothelial transcription factor GATA-2

1

1

High-throughput

0.479

High

703118

TEAD1
Transcriptional enhancer factor TEF-1

1

1

High-throughput

0.479

High

725236

TLX1
T-cell leukemia homeobox protein 1

1

8

High-throughput

0.479

High

772741

MYH9
Myosin-9

1

1

Small-scale

0.479

High

877507

LHX1
LIM/homeobox protein Lhx1

1

20

High-throughput

0.479

High

895698

LHX2
LIM/homeobox protein Lhx2

1

20

High-throughput

0.479

High

904588

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

1010748

EP300
Histone acetyltransferase p300

1

7

High-throughput

0.479

High

1010749

NFIA
Nuclear factor 1 A-type

1

14

High-throughput

0.479

High

1010754

NFIX
Nuclear factor 1 X-type

1

14

High-throughput

0.479

High

1010758

LHX8
LIM/homeobox protein Lhx8

1

20

High-throughput

0.479

High

1010762

BCL9L
B-cell CLL/lymphoma 9-like protein

1

8

High-throughput

0.479

High

1010765

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

4

Small-scale

0.479

High

1010798

ORC6
Origin recognition complex subunit 6

1

1

High-throughput

0.479

High

347643

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

1010769

SOSB2
SOSS complex subunit B2

1

0

Small-scale

0.458

High

1010783

SOSSC
SOSS complex subunit C

1

0

Small-scale

0.458

High

765381

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.445

High

1010755

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

1

High-throughput

0.445

High

1010771

RBM14
RNA-binding protein 14

1

1

High-throughput

0.445

High

1010751

ACACA
Acetyl-CoA carboxylase 1

1

2

Small-scale

0.437

High

1010773

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

2

Small-scale

0.437

High

1010780

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

1

Small-scale

0.437

High

215415

TPD54
Tumor protein D54

1

0

High-throughput

0.426

High

249604

SNX3
Sorting nexin-3

1

0

High-throughput

0.426

High

581511

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

0

High-throughput

0.426

High

855590

CRK
Adapter molecule crk

1

0

High-throughput

0.426

High

1010747

TAGL
Transgelin

1

0

High-throughput

0.426

High

1010778

NAA50
N-alpha-acetyltransferase 50

1

0

High-throughput

0.426

High

1010779

STN1
CST complex subunit STN1

1

0

High-throughput

0.426

High

1010781

TIGAR
Fructose-2,6-bisphosphatase TIGAR

1

0

High-throughput

0.426

High

1010796

SBDS
Ribosome maturation protein SBDS

1

0

High-throughput

0.426

High

96806

E9PB39
Rho guanine nucleotide exchange factor 10

1

3

High-throughput

0.407

High

379089

IGKC
Immunoglobulin kappa constant

1

5

High-throughput

0.407

High

379237

IGHG1
Immunoglobulin heavy constant gamma 1

1

5

High-throughput

0.407

High

379346

IGHG2
Immunoglobulin heavy constant gamma 2

1

6

High-throughput

0.407

High

380531

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

3

High-throughput

0.407

High

63134

CL18A
C-type lectin domain family 18 member A

3

0

High-throughput

0.347

High

369856

CO3
Complement C3

1

0

High-throughput

0.279

Low

390884

TRFE
Serotransferrin

1

0

High-throughput

0.279

Low

590988

LOX15
Polyunsaturated fatty acid lipoxygenase ALOX15

1

0

High-throughput

0.279

Low

627122

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.279

Low

833095

MNDA
Myeloid cell nuclear differentiation antigen

1

0

High-throughput

0.279

Low

1010753

TRI29
Tripartite motif-containing protein 29

1

0

High-throughput

0.279

Low

717062

ECHM
Enoyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.232

Low

770450

SPRE
Sepiapterin reductase

1

0

High-throughput

0.232

Low

1010756

THTR
Thiosulfate sulfurtransferase

1

0

High-throughput

0.232

Low

1010770

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.232

Low

1010784

RBM12
RNA-binding protein 12

1

0

High-throughput

0.232

Low

1010785

CYRIB
CYFIP-related Rac1 interactor B

1

0

High-throughput

0.232

Low

1010795

SGT1
Protein SGT1 homolog

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025