HitPredict

Interactor 1: LHX8 (Q68G74)
LIM/homeobox protein Lhx8 (LIM homeobox protein 8)
Gene: LHX8

Interactor 2: SSBP4 (Q9BWG4)
Single-stranded DNA-binding protein 4
Gene: SSBP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 356 Hs			1 385
+	Hs
		1229373 LHX8_HUMAN (1-356): 6.63e-82: 255: 100.00		SSBP3_HUMAN (6-385): 7.35e-54: 184: 70.03
+	Hs
		1416161 LHX6_HUMAN (15-344): 3.95e-63: 207: 55.72		SSBP4_HUMAN (1-385): 6.03e-71: 228: 100.00
+	Hs
		877555 LHX1_HUMAN (74-353): 9.57e-58: 194: 25.89		SSBP4_HUMAN (1-385): 6.03e-71: 228: 100.00
+	Hs
		1416155 LHX9_HUMAN (66-341): 1.34e-56: 191: 28.79		SSBP4_HUMAN (1-385): 6.03e-71: 228: 100.00
+	Hs
		961490 ISL1_HUMAN (62-336): 3.05e-57: 191: 30.10		SSBP4_HUMAN (1-385): 6.03e-71: 228: 100.00
+	Hs
		895791 LHX2_HUMAN (74-354): 2.71e-56: 190: 24.93		SSBP4_HUMAN (1-385): 6.03e-71: 228: 100.00
+	Hs
		1010758 LHX8_HUMAN (1-356): 6.63e-82: 255: 100.00		SSBP2_HUMAN (1-385): 1.3e-43: 156: 69.51
+	Hs
		1416433 LHX6_HUMAN (15-344): 3.95e-63: 207: 55.72		SSBP3_HUMAN (6-385): 7.35e-54: 184: 70.03
+	Hs
		877557 LHX1_HUMAN (74-353): 9.57e-58: 194: 25.89		SSBP3_HUMAN (6-385): 7.35e-54: 184: 70.03
+	Mm
		1423948 LHX2_MOUSE (74-354): 2.15e-57: 193: 25.22		SSBP3_MOUSE (6-385): 7.35e-54: 184: 70.03
+	Hs
		1416425 LHX9_HUMAN (66-341): 1.34e-56: 191: 28.79		SSBP3_HUMAN (6-385): 7.35e-54: 184: 70.03
+	Hs
		961491 ISL1_HUMAN (62-336): 3.05e-57: 191: 30.10		SSBP3_HUMAN (6-385): 7.35e-54: 184: 70.03
+	Mm
		961502 ISL1_MOUSE (62-336): 3.05e-57: 191: 30.10		SSBP3_MOUSE (6-385): 7.35e-54: 184: 70.03
+	Hs
		895792 LHX2_HUMAN (74-354): 2.71e-56: 190: 24.93		SSBP3_HUMAN (6-385): 7.35e-54: 184: 70.03
+	Hs
		1010792 LHX6_HUMAN (15-344): 3.95e-63: 207: 55.72		SSBP2_HUMAN (1-385): 1.3e-43: 156: 69.51
+	Mm
		1423892 LHX2_MOUSE (74-354): 2.15e-57: 193: 25.22		SSBP2_MOUSE (1-385): 5.08e-44: 157: 69.77
+	Hs
		877507 LHX1_HUMAN (74-353): 9.57e-58: 194: 25.89		SSBP2_HUMAN (1-385): 1.3e-43: 156: 69.51
+	Mm
		961501 ISL1_MOUSE (62-336): 3.05e-57: 191: 30.10		SSBP2_MOUSE (1-385): 5.08e-44: 157: 69.77
+	Hs
		961475 ISL1_HUMAN (62-336): 3.05e-57: 191: 30.10		SSBP2_HUMAN (1-385): 1.3e-43: 156: 69.51
+	Hs
		895698 LHX2_HUMAN (74-354): 2.71e-56: 190: 24.93		SSBP2_HUMAN (1-385): 1.3e-43: 156: 69.51