HitPredict

Interactor 1: SSBP2 (P81877)
Single-stranded DNA-binding protein 2 (Sequence-specific single-stranded-DNA-binding protein 2)
Gene: SSBP2

Interactor 2: LMO3 (Q8TAP4)
LIM domain only protein 3 (LMO-3) (Neuronal-specific transcription factor DAT1) (Rhombotin-3)
Gene: LMO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 361 Hs			1 145
+	Hs
		1010768 SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00		ISL2_HUMAN (11-131): 2.08e-48: 160: 39.34
+	Mm
		1423864 SSBP2_MOUSE (1-361): 8.32e-60: 198: 99.72		ISL2_MOUSE (11-131): 2.83e-48: 160: 39.34
+	Hs
		1010758 SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00		LHX8_HUMAN (12-132): 3.06e-46: 155: 39.67
+	Hs
		681787 SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00		RBTN2_HUMAN (13-133): 8.24e-46: 148: 60.33
+	Hs
		965432 SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00		LMO4_HUMAN (11-142): 2.91e-41: 137: 50.76
+	Mm
		965536 SSBP2_MOUSE (1-361): 8.32e-60: 198: 99.72		LMO4_MOUSE (11-142): 2.91e-41: 137: 50.76
+	Hs
		961475 SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00		ISL1_HUMAN (4-132): 5.58e-39: 136: 36.15
+	Mm
		961501 SSBP2_MOUSE (1-361): 8.32e-60: 198: 99.72		ISL1_MOUSE (4-132): 5.58e-39: 136: 36.15
+	Mm
		1363385 SSBP2_MOUSE (1-361): 8.32e-60: 198: 99.72		RBTN1_MOUSE (1-145): 8.6e-40: 132: 89.66
+	Mm
		1297636 SSBP2_MOUSE (1-361): 8.32e-60: 198: 99.72		LMO3_MOUSE (1-145): 2.03e-36: 123: 100.00
+	Hs
		682020 SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00		RBTN1_HUMAN (1-133): 4.57e-36: 123: 95.49
+	Hs
		1010767 SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00		LHX4_HUMAN (4-83): 1.38e-11: 62.7: 17.28
+	Hs
		253011 SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00		LMX1B_HUMAN (4-72): 3.9e-11: 61.2: 25.71
+	Mm
		312710 SSBP2_MOUSE (1-361): 8.32e-60: 198: 99.72		LMX1B_MOUSE (4-72): 3.99e-11: 61.2: 25.71
+	Mm
		1423890 SSBP2_MOUSE (1-361): 8.32e-60: 198: 99.72		LMX1A_MOUSE (4-72): 6.19e-11: 60.8: 22.86
+	Hs
		1010789 SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00		LHX3_HUMAN (4-74): 9.36e-11: 60: 19.44
+	Hs
		877507 SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00		LHX1_HUMAN (4-78): 9.53e-11: 60: 25.00
+	Mm
		1423892 SSBP2_MOUSE (1-361): 8.32e-60: 198: 99.72		LHX2_MOUSE (5-78): 2.48e-10: 58.8: 22.67
+	Hs
		895698 SSBP2_HUMAN (1-361): 6.04e-60: 198: 100.00		LHX2_HUMAN (5-78): 3.79e-10: 58.5: 22.67
+	Mm
		1423891 SSBP2_MOUSE (1-361): 8.32e-60: 198: 99.72		LHX9_MOUSE (5-75): 8.3e-10: 57.3: 23.61