HitPredict

Interactor 1: E9PMD8 (E9PMD8)
Proteasome 26S subunit, ATPase 3
Gene: PSMC3

Interactor 2: PSMD7 (P51665)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
Gene: PSMD7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	JAB~Prot_ATP_ID_OB_C
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 301 Hs			1 324
+	Dm
		684544 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSMD7_DROME (3-323): 3.84e-118: 345: 75.54
+	Dm
		684558 Q9V3V6_DROME (34-301): 1.28e-69: 223: 85.82		PSMD7_DROME (3-323): 3.84e-118: 345: 75.54
+	Dm
		198024 PRS8_DROME (55-300): 1.63e-68: 220: 34.82		PSMD7_DROME (3-323): 3.84e-118: 345: 75.54
+	Hs
		610269 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSMD7_HUMAN (1-285): 5.27e-110: 324: 100.00
+	Dm
		684551 Q7KMQ0_DROME (14-300): 9.89e-68: 218: 31.36		PSMD7_DROME (3-323): 3.84e-118: 345: 75.54
+	Dm
		684560 Q9V405_DROME (15-301): 6.6e-67: 216: 33.10		PSMD7_DROME (3-323): 3.84e-118: 345: 75.54
+	Hs
		778636 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSMD7_HUMAN (1-285): 5.27e-110: 324: 100.00
+	Hs
		906494 PRS4_HUMAN (18-301): 3.79e-68: 220: 36.81		PSMD7_HUMAN (1-285): 5.27e-110: 324: 100.00
+	Sc
		750795 PRS6A_YEAST (24-301): 2.46e-68: 220: 65.85		RPN8_YEAST (7-322): 1.4e-99: 298: 47.01
+	Sp
		785689 PRS4_SCHPO (51-301): 6.16e-85: 263: 38.04		RPN11_SCHPO (7-217): 2.02e-50: 171: 19.26
+	Dm
		874995 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSDE_DROME (5-142): 5.82e-28: 112: 24.31
+	Hs
		778747 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		CSN5_HUMAN (7-160): 1.07e-41: 149: 19.38
+	Hs
		137951 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSDE_HUMAN (5-142): 6.83e-28: 112: 24.31
+	Hs
		137990 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSDE_HUMAN (5-142): 6.83e-28: 112: 24.31
+	Dm
		1463622 Q9V3V6_DROME (34-301): 1.28e-69: 223: 85.82		PSDE_DROME (5-142): 5.82e-28: 112: 24.31
+	Hs
		138051 PRS4_HUMAN (18-301): 3.79e-68: 220: 36.81		PSDE_HUMAN (5-142): 6.83e-28: 112: 24.31
+	Dm
		198064 PRS8_DROME (55-300): 1.63e-68: 220: 34.82		PSDE_DROME (5-142): 5.82e-28: 112: 24.31
+	Dm
		1267697 Q7KMQ0_DROME (14-300): 9.89e-68: 218: 31.36		PSDE_DROME (5-142): 5.82e-28: 112: 24.31
+	Dm
		1463624 Q9V405_DROME (15-301): 6.6e-67: 216: 33.10		PSDE_DROME (5-142): 5.82e-28: 112: 24.31
+	Hs
		138008 PRS6B_HUMAN (9-301): 3.83e-66: 214: 34.13		PSDE_HUMAN (5-142): 6.83e-28: 112: 24.31