HitPredict

Interactor 1: E9PMD8 (E9PMD8)
Proteasome 26S subunit, ATPase 3
Gene: PSMC3

Interactor 2: PSMD4 (P55036)
26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (Antisecretory factor 1) (AF) (ASF) (Multiubiquitin chain-binding protein)
Gene: PSMD4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 301 Hs			1 377
+	Hs
		610279 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSMD4_HUMAN (1-364): 0: 530: 100.00
+	Hs
		610372 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		Q5VWC4_HUMAN (1-364): 0: 525: 99.18
+	Hs
		778643 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSMD4_HUMAN (1-364): 0: 530: 100.00
+	Hs
		58802 PRS4_HUMAN (18-301): 3.79e-68: 220: 36.81		PIPSL_HUMAN (3-364): 0: 532: 92.54
+	Hs
		933603 PRS4_HUMAN (18-301): 3.79e-68: 220: 36.81		PSMD4_HUMAN (1-364): 0: 530: 100.00
+	Hs
		968730 PRS4_HUMAN (18-301): 3.79e-68: 220: 36.81		Q5VWC4_HUMAN (1-364): 0: 525: 99.18
+	Hs
		851276 PRS6B_HUMAN (9-301): 3.83e-66: 214: 34.13		PSMD4_HUMAN (1-364): 0: 530: 100.00
+	Hs
		851347 PRS6B_HUMAN (9-301): 3.83e-66: 214: 34.13		Q5VWC4_HUMAN (1-364): 0: 525: 99.18
+	Xl
		857268 PRS8_XENLA (57-301): 1.29e-64: 211: 37.40		Q4V845_XENLA (1-364): 0: 519: 91.48
+	Dm
		874957 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSMD4_DROME (1-359): 6.77e-149: 428: 57.40
+	Hs
		933590 TERA_HUMAN (5-301): 3.82e-46: 167: 24.04		PSMD4_HUMAN (1-364): 0: 530: 100.00
+	Ce
		263832 PRS6B_CAEEL (45-301): 6.54e-86: 265: 36.58		PSMD4_CAEEL (1-372): 6.28e-116: 342: 44.97
+	Sp
		314151 PRS4_SCHPO (51-301): 6.16e-85: 263: 38.04		RPN10_SCHPO (1-245): 5.13e-104: 308: 45.75
+	At
		933563 PRS4A_ARATH (61-301): 2.12e-49: 171: 39.00		PSMD4_ARATH (1-377): 4.17e-138: 400: 41.32
+	Sp
		152922 PRS6A_SCHPO (33-301): 3.54e-64: 210: 70.37		RPN10_SCHPO (1-245): 5.13e-104: 308: 45.75
+	Sc
		750656 PRS6A_YEAST (24-301): 2.46e-68: 220: 65.85		RPN10_YEAST (1-224): 1.27e-98: 295: 49.15
+	Sc
		750840 PRS6B_YEAST (18-301): 7.19e-65: 211: 31.47		RPN10_YEAST (1-224): 1.27e-98: 295: 49.15
+	Sc
		806734 PRS4_YEAST (129-301): 4.72e-51: 175: 50.29		RPN10_YEAST (1-224): 1.27e-98: 295: 49.15