Interactor 1: TIE2 (Q02763)
Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)
Gene: TEK
Interactor 2: TIE2 (Q02763)
Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)
Gene: TEK
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.41 | 1.00 | 0.647 |
The method score is based on:
Property | Details |
---|---|
Experiments | 26285778 |
Identification Methods | enzymatic study |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | fn3~fn3, PK_Tyr_Ser-Thr~fn3, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr |
Common GO terms | GO:0001525 - angiogenesis GO:0001666 - response to hypoxia GO:0001934 - positive regulation of protein phosphorylation GO:0001935 - endothelial cell proliferation GO:0001938 - positive regulation of endothelial cell proliferation and 48 others more... |
Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024