HitPredict

Interactor 1: KMT2A (Q03164)
Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]
Gene: KMT2A

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 3969 Hs			1 779
+	Hs
		1080342 EZH2_HUMAN (3450-3951): 9.4e-105: 357: 18.54		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		165717 SET1A_HUMAN (3695-3969): 8.18e-56: 218: 34.58		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		596407 EZH2_HUMAN (3450-3951): 9.4e-105: 357: 18.54		RASA1_HUMAN (72-437): 2.74e-44: 174: 11.32
+	Hs
		331800 NSD2_HUMAN (3752-3968): 7.27e-60: 231: 27.23		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28