HitPredict

Interactor 1: PP2AB (P62714)
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16)
Gene: PPP2CB

Interactor 2: 2ABB (Q00005)
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PP2A subunit B isoform B55-beta) (PP2A subunit B isoform PR55-beta) (PP2A subunit B isoform R2-beta) (PP2A subunit B isoform beta)
Gene: PPP2R2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.701

Property	Details
Experiments	28330616, 33961781, 19156129, unassigned3799
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000159 - protein phosphatase type 2A complex GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 309 Hs			1 443
+	Hs
		994178 PP2AA_HUMAN (1-309): 0: 533: 97.41		2ABB_HUMAN (1-443): 0: 825: 100.00
+	Hs
		977617 PP2AB_HUMAN (1-309): 0: 533: 100.00		2ABG_HUMAN (1-443): 0: 808: 87.13
+	Hs
		994427 PP2AA_HUMAN (1-309): 0: 533: 97.41		2ABG_HUMAN (1-443): 0: 808: 87.13
+	Hs
		951963 PP4C_HUMAN (4-309): 0: 512: 64.50		2ABB_HUMAN (1-443): 0: 825: 100.00
+	Xl
		51259 Q92140_XENLA (1-309): 0: 532: 98.06		2ABB_XENLA (6-443): 0: 801: 93.15
+	Xl
		51248 Q8AVH9_XENLA (1-309): 0: 530: 97.41		2ABB_XENLA (6-443): 0: 801: 93.15
+	Hs
		952034 PP4C_HUMAN (4-309): 0: 512: 64.50		2ABG_HUMAN (1-443): 0: 808: 87.13
+	Hs
		977520 PP2AB_HUMAN (1-309): 0: 533: 100.00		2ABD_HUMAN (21-443): 0: 783: 87.94
+	Hs
		994262 PP2AA_HUMAN (1-309): 0: 533: 97.41		2ABD_HUMAN (21-443): 0: 783: 87.94
+	Hs
		977455 PP2AB_HUMAN (1-309): 0: 533: 100.00		2ABA_HUMAN (19-443): 0: 782: 88.47
+	Mm
		977637 PP2AB_MOUSE (1-309): 0: 533: 100.00		2ABA_MOUSE (19-443): 0: 782: 88.47
+	Hs
		991006 PP2AA_HUMAN (1-309): 0: 533: 97.41		2ABA_HUMAN (19-443): 0: 782: 88.47
+	Xl
		1235167 Q8AVH9_XENLA (1-309): 0: 530: 97.41		Q6IRD3_XENLA (18-443): 0: 770: 86.15
+	Hs
		951991 PP4C_HUMAN (4-309): 0: 512: 64.50		2ABD_HUMAN (21-443): 0: 783: 87.94
+	Hs
		951956 PP4C_HUMAN (4-309): 0: 512: 64.50		2ABA_HUMAN (19-443): 0: 782: 88.47
+	Dm
		661919 PP2A_DROME (1-309): 0: 528: 94.50		2ABA_DROME (19-441): 0: 759: 79.20
+	Ce
		111868 PP2A_CAEEL (3-309): 0: 523: 89.58		2AB1_CAEEL (17-440): 0: 678: 65.07
+	Sp
		661362 PP2A2_SCHPO (5-309): 0: 508: 79.02		2ABA_SCHPO (1-439): 0: 644: 54.64
+	Sc
		660876 PP2A2_YEAST (9-309): 0: 531: 76.08		2ABA_YEAST (20-367): 0: 550: 57.14
+	Sc
		660812 PP2A1_YEAST (7-309): 0: 518: 74.92		2ABA_YEAST (20-367): 0: 550: 57.14