HitPredict

Interactor 1: RUB1 (Q03919)
NEDD8-like protein RUB1 (Related to ubiquitin protein 1) (Ubiquitin-like protein RUB1)
Gene: RUB1

Interactor 2: UBA3 (Q99344)
NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (RUB1-activating enzyme E1) (Ubiquitin-activating enzyme E1 3) (Ubiquitin-like protein-activating enzyme)
Gene: UBA3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	9545234
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ThiF~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0045116 - protein neddylation
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 77 Sc			1 299
+	Hs
		1079547 NEDD8_HUMAN (1-76): 1.61e-34: 113: 59.21		UBA3_HUMAN (3-299): 6.76e-113: 335: 41.94
+	Sc
		477515 UBI4P_YEAST (1-76): 1.13e-16: 73.9: 52.63		UBA3_YEAST (1-299): 8.99e-106: 311: 100.00
+	Hs
		1079620 NEDD8_HUMAN (1-76): 1.61e-34: 113: 59.21		SAE2_HUMAN (4-263): 4.21e-73: 238: 31.56
+	Sc
		477271 UBI4P_YEAST (1-76): 1.13e-16: 73.9: 52.63		UBA4_YEAST (2-161): 4.2e-48: 167: 29.01
+	Hs
		607051 RS27A_HUMAN (1-76): 3.48e-37: 123: 52.63		UBA1_HUMAN (3-143): 7.98e-24: 103: 24.82
+	Sc
		408274 RS31_YEAST (1-70): 2.28e-30: 105: 50.00		UBA1_YEAST (3-144): 8.06e-21: 94.4: 23.78
+	Sc
		477133 UBI4P_YEAST (1-76): 1.13e-16: 73.9: 52.63		UBA1_YEAST (3-144): 8.06e-21: 94.4: 23.78