HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: SWAHC (Q53LP3)
Ankyrin repeat domain-containing protein SOWAHC (Ankyrin repeat domain-containing protein 57) (Protein sosondowah homolog C)
Gene: SOWAHC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.675

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 525
+	Hs
		988416 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		SWAHC_HUMAN (1-525): 1.97e-120: 365: 100.00
+	Hs
		962122 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		SWAHC_HUMAN (1-525): 1.97e-120: 365: 100.00
+	Hs
		1015491 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		SWAHC_HUMAN (1-525): 1.97e-120: 365: 100.00
+	Hs
		466293 RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16		SWAHC_HUMAN (1-525): 1.97e-120: 365: 100.00
+	Hs
		988324 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		ANK3_HUMAN (272-522): 8.43e-41: 160: 16.19
+	Hs
		961998 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		ANK3_HUMAN (272-522): 8.43e-41: 160: 16.19
+	Hs
		977967 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		ANK3_HUMAN (272-522): 8.43e-41: 160: 16.19
+	Hs
		988289 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		ANK2_HUMAN (261-522): 9.95e-39: 153: 14.82
+	Hs
		1015396 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		ANK3_HUMAN (272-522): 8.43e-41: 160: 16.19
+	Hs
		295481 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		PSD10_HUMAN (275-408): 8.83e-40: 145: 26.12
+	Hs
		962216 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		ANS1B_HUMAN (266-509): 9.57e-34: 138: 14.54
+	Hs
		962478 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		Q9H4D1_HUMAN (39-330): 1.3e-30: 128: 11.48
+	Hs
		988816 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		KDIS_HUMAN (10-305): 4.55e-20: 96.5: 9.73
+	Hs
		943894 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		RIPK4_HUMAN (5-271): 3.17e-20: 96.5: 11.07
+	Hs
		962626 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		KDIS_HUMAN (10-305): 4.55e-20: 96.5: 9.73
+	Hs
		978398 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		KDIS_HUMAN (10-305): 4.55e-20: 96.5: 9.73
+	Hs
		581370 RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57		KDIS_HUMAN (10-305): 4.55e-20: 96.5: 9.73
+	Hs
		1015901 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		KDIS_HUMAN (10-305): 4.55e-20: 96.5: 9.73
+	Hs
		988335 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		ILK_HUMAN (284-382): 7.26e-16: 81.9: 29.29
+	Hs
		962014 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		ILK_HUMAN (284-382): 7.26e-16: 81.9: 29.29