HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: KANK2 (Q63ZY3)
KN motif and ankyrin repeat domain-containing protein 2 (Ankyrin repeat domain-containing protein 25) (Matrix-remodeling-associated protein 3) (SRC-1-interacting protein) (SIP) (SRC-interacting protein) (SRC1-interacting protein)
Gene: KANK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras
Common GO terms	GO:0006915 - apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 851
+	Hs
		581108 RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57		KANK2_HUMAN (1-851): 0: 546: 100.00
+	Hs
		988289 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		ANK2_HUMAN (141-851): 2.6e-85: 301: 13.51
+	Hs
		988324 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		ANK3_HUMAN (141-848): 2.49e-85: 301: 12.36
+	Hs
		961998 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		ANK3_HUMAN (141-848): 2.49e-85: 301: 12.36
+	Hs
		977967 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		ANK3_HUMAN (141-848): 2.49e-85: 301: 12.36
+	Hs
		1015396 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		ANK3_HUMAN (141-848): 2.49e-85: 301: 12.36
+	Hs
		295481 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		PSD10_HUMAN (675-851): 3.58e-47: 169: 21.47
+	Hs
		988816 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		962626 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		978398 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		581370 RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		1015901 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		466521 RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		962478 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		Q9H4D1_HUMAN (286-768): 1.68e-28: 124: 14.13
+	Hs
		943894 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		RIPK4_HUMAN (246-768): 1.04e-26: 118: 13.97
+	Hs
		988774 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		RAI14_HUMAN (710-831): 9e-21: 100: 27.05
+	Hs
		962575 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		RAI14_HUMAN (710-831): 9e-21: 100: 27.05
+	Hs
		978363 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		RAI14_HUMAN (710-831): 9e-21: 100: 27.05
+	Hs
		1015865 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		RAI14_HUMAN (710-831): 9e-21: 100: 27.05
+	Mm
		86305 RAC3_MOUSE (1-179): 5.41e-75: 225: 57.54		CTTB2_MOUSE (13-724): 6.94e-16: 84.7: 12.47