HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (EC 3.6.5.2) (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: KANK2 (Q63ZY3)
KN motif and ankyrin repeat domain-containing protein 2 (Ankyrin repeat domain-containing protein 25) (Matrix-remodeling-associated protein 3) (SRC-1-interacting protein) (SIP) (SRC-interacting protein) (SRC1-interacting protein)
Gene: KANK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 851
+	Hs
		988289 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		ANK2_HUMAN (141-851): 2.6e-85: 301: 13.51
+	Hs
		988324 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		ANK3_HUMAN (141-848): 2.49e-85: 301: 12.36
+	Hs
		1015396 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		ANK3_HUMAN (141-848): 2.49e-85: 301: 12.36
+	Hs
		955105 CDC42_HUMAN (1-192): 1.66e-78: 234: 68.75		ANK3_HUMAN (141-848): 2.49e-85: 301: 12.36
+	Hs
		961998 RHOA_HUMAN (5-192): 1.59e-77: 231: 54.26		ANK3_HUMAN (141-848): 2.49e-85: 301: 12.36
+	Hs
		988816 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		581370 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		295481 RHOA_HUMAN (5-192): 1.59e-77: 231: 54.26		PSD10_HUMAN (675-851): 3.58e-47: 169: 21.47
+	Hs
		601494 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		953754 RAC3_HUMAN (1-191): 4.97e-80: 238: 89.01		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		1015901 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		955746 CDC42_HUMAN (1-192): 1.66e-78: 234: 68.75		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		962478 RHOA_HUMAN (5-192): 1.59e-77: 231: 54.26		Q9H4D1_HUMAN (286-768): 1.68e-28: 124: 14.13
+	Hs
		988774 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		RAI14_HUMAN (710-831): 9e-21: 100: 27.05
+	Hs
		943894 RHOA_HUMAN (5-192): 1.59e-77: 231: 54.26		RIPK4_HUMAN (246-768): 1.04e-26: 118: 13.97
+	Hs
		601474 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		RAI14_HUMAN (710-831): 9e-21: 100: 27.05
+	Hs
		953720 RAC3_HUMAN (1-191): 4.97e-80: 238: 89.01		RAI14_HUMAN (710-831): 9e-21: 100: 27.05
+	Hs
		1015865 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		RAI14_HUMAN (710-831): 9e-21: 100: 27.05
+	Hs
		955693 CDC42_HUMAN (1-192): 1.66e-78: 234: 68.75		RAI14_HUMAN (710-831): 9e-21: 100: 27.05
+	Mm
		86305 RAC3_MOUSE (1-191): 4.97e-80: 238: 89.01		CTTB2_MOUSE (13-724): 6.94e-16: 84.7: 12.47