HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: PHAR4 (Q8IZ21)
Phosphatase and actin regulator 4
Gene: PHACTR4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007266 - Rho protein signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 702
+	Hs
		988514 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		PHAR4_HUMAN (1-702): 2.05e-74: 256: 100.00
+	Hs
		962252 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		PHAR4_HUMAN (1-702): 2.05e-74: 256: 100.00
+	Hs
		581158 RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57		PHAR4_HUMAN (1-702): 2.05e-74: 256: 100.00
+	Hs
		1015586 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		PHAR4_HUMAN (1-702): 2.05e-74: 256: 100.00
+	Hs
		955363 CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49		PHAR4_HUMAN (1-702): 2.05e-74: 256: 100.00
+	Hs
		988300 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		DYST_HUMAN (354-699): 3.25e-41: 165: 15.13
+	Hs
		581002 RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57		DYST_HUMAN (354-699): 3.25e-41: 165: 15.13
+	Hs
		273619 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		PHAR2_HUMAN (8-702): 2.45e-39: 156: 36.90
+	Hs
		176260 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		SYNJ2_HUMAN (51-511): 1.05e-26: 118: 13.90
+	Hs
		176256 RAC3_HUMAN (1-179): 5.41e-75: 225: 57.54		SYNJ2_HUMAN (51-511): 1.05e-26: 118: 13.90
+	Hs
		319060 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		K0754_HUMAN (147-657): 4.44e-20: 98.1: 11.35
+	Hs
		319057 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		K0754_HUMAN (147-657): 4.44e-20: 98.1: 11.35
+	Hs
		319059 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		K0754_HUMAN (147-657): 4.44e-20: 98.1: 11.35
+	Hs
		319049 RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57		K0754_HUMAN (147-657): 4.44e-20: 98.1: 11.35
+	Hs
		319064 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		K0754_HUMAN (147-657): 4.44e-20: 98.1: 11.35
+	Hs
		319046 RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16		K0754_HUMAN (147-657): 4.44e-20: 98.1: 11.35
+	Hs
		319056 RAC3_HUMAN (1-179): 5.41e-75: 225: 57.54		K0754_HUMAN (147-657): 4.44e-20: 98.1: 11.35
+	Ce
		145082 RAC1_CAEEL (1-196): 3.83e-80: 238: 53.57		UNC89_CAEEL (2-256): 5.58e-14: 78.4: 12.88
+	Ce
		110130 G5EBV3_CAEEL (2-196): 7.16e-76: 227: 48.72		UNC89_CAEEL (2-256): 5.58e-14: 78.4: 12.88
+	Ce
		145089 RHO1_CAEEL (1-196): 4.79e-75: 225: 78.57		UNC89_CAEEL (2-256): 5.58e-14: 78.4: 12.88