HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: BRD8 (Q9H0E9)
Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120)
Gene: BRD8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 103 Hs			1 1235
+	Hs
		979567 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		BPTF_HUMAN (130-1222): 9.47e-42: 170: 9.46
+	Hs
		980083 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		KAT2B_HUMAN (1075-1209): 2.95e-37: 154: 23.70
+	Hs
		980503 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		BAZ2A_HUMAN (125-815): 1.94e-34: 146: 11.39
+	Dm
		1014820 H4_DROME (1-103): 4.53e-48: 150: 99.03		NU301_DROME (67-820): 3.92e-34: 145: 11.11
+	Dm
		1014796 H4_DROME (1-103): 4.53e-48: 150: 99.03		Q9V9T4_DROME (587-830): 7.51e-32: 137: 16.73
+	Hs
		180769 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		TIF1A_HUMAN (846-1228): 2.48e-31: 135: 14.11
+	Sp
		480433 H4_SCHPO (18-103): 4.89e-42: 135: 89.54		GCN5_SCHPO (603-815): 2.61e-36: 145: 17.84
+	Hs
		980379 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		BRD7_HUMAN (1039-1212): 6.56e-29: 126: 17.32
+	Hs
		979908 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		PB1_HUMAN (988-1226): 1.68e-22: 107: 15.51
+	Hs
		639705 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		TAF1_HUMAN (1002-1220): 4.19e-22: 106: 15.32
+	Sp
		480426 H4_SCHPO (18-103): 4.89e-42: 135: 89.54		YK82_SCHPO (843-1204): 9.27e-26: 116: 13.90
+	Dm
		567628 H4_DROME (1-103): 4.53e-48: 150: 99.03		FSH_DROME (391-890): 1.22e-20: 101: 11.83
+	Hs
		979968 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		TAF1L_HUMAN (1101-1206): 4.27e-19: 96.3: 21.70
+	Hs
		979856 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		BRWD3_HUMAN (1049-1232): 4.64e-19: 95.9: 18.28
+	Hs
		903303 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		SMCA4_HUMAN (1057-1208): 7.29e-19: 95.5: 13.84
+	Zm
		19410 A0A1D6IAU4_MAIZE (1-103): 4.99e-53: 163: 98.06		A0A1D6HCG5_MAIZE (1084-1221): 7.67e-15: 81.5: 27.14
+	Hs
		980051 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		PHIP_HUMAN (1059-1206): 1.2e-14: 81.5: 15.23
+	Hs
		980082 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		KAT2A_HUMAN (684-810): 1.1e-12: 74.9: 17.32
+	Hs
		980078 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		CBP_HUMAN (105-563): 8.91e-10: 65.7: 7.96
+	Hs
		979558 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		EP300_HUMAN (150-707): 9.24e-09: 62.4: 8.45