HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	27462807
Identification Methods	pull down, cross-linking study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 1972
+	Hs
		1129608 H2B2E_HUMAN (1-126): 5.64e-54: 166: 99.21		MDC1_HUMAN (24-1848): 6.05e-94: 341: 11.23
+	Hs
		1129680 H2B1H_HUMAN (1-126): 5.52e-54: 166: 99.21		MDC1_HUMAN (24-1848): 6.05e-94: 341: 11.23
+	Hs
		980769 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		MDC1_HUMAN (24-1848): 6.05e-94: 341: 11.23
+	Hs
		1208861 H2B2F_HUMAN (1-126): 2.22e-54: 168: 98.41		TITIN_HUMAN (5-1527): 2.75e-30: 134: 9.47
+	Hs
		659923 H2B1O_HUMAN (1-126): 2.89e-54: 167: 98.41		TITIN_HUMAN (5-1527): 2.75e-30: 134: 9.47
+	Hs
		1163098 H2B2E_HUMAN (1-126): 5.64e-54: 166: 99.21		TITIN_HUMAN (5-1527): 2.75e-30: 134: 9.47
+	Hs
		1361886 H2B1H_HUMAN (1-126): 5.52e-54: 166: 99.21		TITIN_HUMAN (5-1527): 2.75e-30: 134: 9.47
+	Hs
		256937 H2B1K_HUMAN (1-126): 1.31e-53: 166: 99.21		TITIN_HUMAN (5-1527): 2.75e-30: 134: 9.47
+	Hs
		943396 H2BFS_HUMAN (1-126): 1.03e-53: 166: 97.62		TITIN_HUMAN (5-1527): 2.75e-30: 134: 9.47
+	Hs
		980966 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		TITIN_HUMAN (5-1527): 2.75e-30: 134: 9.47
+	Hs
		62778 H2B1H_HUMAN (1-126): 5.52e-54: 166: 99.21		XIRP2_HUMAN (66-1458): 1.46e-25: 118: 9.42
+	Hs
		1372265 H2B1H_HUMAN (1-126): 5.52e-54: 166: 99.21		ZN469_HUMAN (29-1459): 5.51e-23: 110: 9.99
+	Hs
		1208916 H2B2F_HUMAN (1-126): 2.22e-54: 168: 98.41		PCLO_HUMAN (929-1774): 1.06e-19: 99.2: 8.14
+	Hs
		659962 H2B1O_HUMAN (1-126): 2.89e-54: 167: 98.41		PCLO_HUMAN (929-1774): 1.06e-19: 99.2: 8.14
+	Hs
		1163322 H2B2E_HUMAN (1-126): 5.64e-54: 166: 99.21		PCLO_HUMAN (929-1774): 1.06e-19: 99.2: 8.14
+	Hs
		1372356 H2B1H_HUMAN (1-126): 5.52e-54: 166: 99.21		PCLO_HUMAN (929-1774): 1.06e-19: 99.2: 8.14
+	Hs
		257024 H2B1K_HUMAN (1-126): 1.31e-53: 166: 99.21		PCLO_HUMAN (929-1774): 1.06e-19: 99.2: 8.14
+	Hs
		449810 H2B1J_HUMAN (1-126): 6.64e-54: 166: 98.41		PCLO_HUMAN (929-1774): 1.06e-19: 99.2: 8.14
+	Hs
		1316402 H2B1H_HUMAN (1-126): 5.52e-54: 166: 99.21		AGRG4_HUMAN (58-1397): 2.31e-15: 84.8: 13.13
+	Hs
		981034 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		MINT_HUMAN (31-1787): 1.04e-11: 72.8: 9.54