HitPredict

Interactor 1: UBE4A (E9Q735)
Ubiquitin conjugation factor E4 A (EC 2.3.2.27)
Gene: UBE4A

Interactor 2: UB2D1 (P61080)
Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)
Gene: Ube2d1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	37429524
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	U-box~UQ_con
Common GO terms	GO:0000209 - protein polyubiquitination GO:0005737 - cytoplasm GO:0006511 - ubiquitin-dependent protein catabolic process GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1028 Mm			1 147
+	Hs
		1121158 UBE4A_HUMAN (1-1028): 0: 1276: 93.81		UB2D4_HUMAN (1-147): 2.21e-83: 243: 91.84
+	Hs
		906664 UBE4A_HUMAN (1-1028): 0: 1276: 93.81		UB2D1_HUMAN (1-147): 5.09e-83: 241: 100.00
+	Hs
		982185 UBE4A_HUMAN (1-1028): 0: 1276: 93.81		UB2D2_HUMAN (1-147): 1.34e-82: 240: 89.12
+	Hs
		957078 UBE4A_HUMAN (1-1028): 0: 1276: 93.81		UB2D3_HUMAN (1-147): 1.54e-81: 238: 88.44
+	Hs
		326942 UBE4B_HUMAN (145-1023): 0: 785: 24.60		UB2D2_HUMAN (1-147): 1.34e-82: 240: 89.12
+	Hs
		326941 UBE4B_HUMAN (145-1023): 0: 785: 24.60		UB2D3_HUMAN (1-147): 1.54e-81: 238: 88.44
+	Sc
		585721 UFD2_YEAST (143-1025): 0: 710: 22.31		UBC4_YEAST (3-147): 9.95e-80: 233: 79.31
+	Zm
		31112 A0A1D6KE36_MAIZE (917-1021): 5.46e-35: 144: 27.50		B4FC97_MAIZE (1-147): 2.79e-83: 242: 76.19
+	At
		762759 CHIP_ARATH (903-1025): 5.64e-31: 125: 20.93		UBC8_ARATH (1-147): 7.99e-83: 241: 76.19
+	At
		762775 CHIP_ARATH (903-1025): 5.64e-31: 125: 20.93		UBC9_ARATH (1-147): 1.86e-82: 240: 77.55
+	At
		762784 CHIP_ARATH (903-1025): 5.64e-31: 125: 20.93		UBC10_ARATH (1-147): 1.84e-82: 240: 76.87
+	Ce
		111253 G5ECY6_CAEEL (900-1027): 1.24e-29: 121: 26.36		UBC2_CAEEL (1-147): 1.25e-82: 241: 89.12
+	Hs
		906827 CHIP_HUMAN (922-1022): 1.44e-29: 121: 31.37		UB2D1_HUMAN (1-147): 5.09e-83: 241: 100.00
+	Hs
		982367 CHIP_HUMAN (922-1022): 1.44e-29: 121: 31.37		UB2D2_HUMAN (1-147): 1.34e-82: 240: 89.12
+	Hs
		957243 CHIP_HUMAN (922-1022): 1.44e-29: 121: 31.37		UB2D3_HUMAN (1-147): 1.54e-81: 238: 88.44
+	Hs
		1397304 CHIP_HUMAN (922-1022): 1.44e-29: 121: 31.37		UB2E2_HUMAN (4-146): 8.22e-75: 223: 62.94
+	Hs
		1381220 CHIP_HUMAN (922-1022): 1.44e-29: 121: 31.37		UB2E3_HUMAN (4-146): 2.8e-74: 221: 62.94
+	Hs
		909412 CHIP_HUMAN (922-1022): 1.44e-29: 121: 31.37		UB2E1_HUMAN (4-146): 1.07e-72: 217: 62.94
+	Zm
		14188 A0A1D6LII0_MAIZE (757-1025): 8.66e-35: 136: 20.56		A0A1D6G0U5_MAIZE (1-113): 6.78e-65: 196: 79.65
+	Hs
		957867 CHIP_HUMAN (922-1022): 1.44e-29: 121: 31.37		UBE2N_HUMAN (4-147): 5.9e-69: 206: 45.83