Interactor 1: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.706

The method score is based on:

Property Details
Experiments 31046837, 20642453, 29541021, unassigned1853, 23075850
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003779 - actin binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 246
Hs

1 2527
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024