HitPredict

Interactor 1: CC141 (E9Q8Q6)
Coiled-coil domain-containing protein 141 (Coiled-coil protein associated with myosin II and DISC1)
Gene: Ccdc141

Interactor 2: HDAC6 (Q9Z2V5)
Protein deacetylase HDAC6 (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) (mHDA2)
Gene: HDAC6

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27737934
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1531 Mm			1 1149
+	Mm
		1296927 Q8BLD3_MOUSE (1-655): 1.19e-59: 220: 99.85		HDAC6_MOUSE (1-1149): 0: 1360: 100.00
+	Mm
		1223386 MYH10_MOUSE (373-1352): 8.06e-29: 128: 10.46		HDAC6_MOUSE (1-1149): 0: 1360: 100.00
+	Hs
		773060 MYH9_HUMAN (6-823): 7.08e-31: 135: 10.67		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		773296 MYH10_HUMAN (4-794): 3.33e-28: 126: 9.30		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		776867 MYH11_HUMAN (385-1406): 1.08e-26: 121: 8.70		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		238832 KALRN_HUMAN (876-1516): 2.83e-20: 100: 12.39		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		1117517 SPTN1_HUMAN (31-951): 5.77e-19: 96.1: 12.27		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		174816 SPTN2_HUMAN (104-1202): 5.46e-17: 89.9: 9.64		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		772785 MYH9_HUMAN (6-823): 7.08e-31: 135: 10.67		HDAC1_HUMAN (470-870): 3.76e-156: 475: 20.75
+	Hs
		772937 MYH9_HUMAN (6-823): 7.08e-31: 135: 10.67		HDAC2_HUMAN (77-488): 7.68e-156: 475: 21.89
+	Hs
		1110177 MYH2_HUMAN (340-1408): 1.31e-29: 130: 8.07		HDAC1_HUMAN (470-870): 3.76e-156: 475: 20.75
+	Hs
		773240 MYH10_HUMAN (4-794): 3.33e-28: 126: 9.30		HDAC2_HUMAN (77-488): 7.68e-156: 475: 21.89
+	Hs
		563054 MYH8_HUMAN (340-1406): 1.77e-27: 124: 7.62		HDAC1_HUMAN (470-870): 3.76e-156: 475: 20.75
+	Hs
		556850 MYH1_HUMAN (340-1406): 2.97e-27: 123: 7.81		HDAC1_HUMAN (470-870): 3.76e-156: 475: 20.75
+	Hs
		773088 MYH9_HUMAN (6-823): 7.08e-31: 135: 10.67		HDAC5_HUMAN (439-878): 9.05e-140: 453: 35.89
+	Mm
		86350 B9EKJ1_MOUSE (31-951): 1.93e-20: 101: 11.78		HDAC4_MOUSE (450-863): 2.04e-144: 464: 39.73
+	Hs
		556922 MYH7_HUMAN (2-539): 5.34e-17: 89.8: 10.11		HDAC1_HUMAN (470-870): 3.76e-156: 475: 20.75
+	Mm
		597655 SPTN1_MOUSE (31-951): 4.67e-19: 96.5: 12.06		HDAC4_MOUSE (450-863): 2.04e-144: 464: 39.73
+	Mm
		86345 B9EKJ1_MOUSE (31-951): 1.93e-20: 101: 11.78		Q3UJF1_MOUSE (402-878): 1.21e-140: 455: 33.33
+	Mm
		597667 SPTN1_MOUSE (31-951): 4.67e-19: 96.5: 12.06		HDAC5_MOUSE (402-878): 1.11e-140: 455: 33.33