HitPredict

Interactor 1: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051020 - GTPase binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 1298
+	Hs
		965276 NLE1_HUMAN (46-340): 4.02e-88: 274: 21.22		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Hs
		965071 WDR5B_HUMAN (89-340): 2.84e-84: 259: 26.17		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Hs
		964797 WDR5_HUMAN (130-340): 4.37e-68: 218: 27.23		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Mm
		983625 GBB1_MOUSE (1-340): 1.7e-106: 316: 100.00		RACK1_MOUSE (82-346): 9.31e-42: 158: 9.28
+	Hs
		965151 WDR5_HUMAN (130-340): 4.37e-68: 218: 27.23		SNR40_HUMAN (45-334): 1.8e-54: 196: 12.04
+	At
		879962 GBB_ARATH (132-340): 8.36e-39: 143: 23.32		GPLPC_ARATH (12-295): 3.72e-69: 237: 10.10
+	Hs
		845264 WDR5_HUMAN (130-340): 4.37e-68: 218: 27.23		LIS1_HUMAN (123-363): 2.02e-35: 142: 12.30
+	Hs
		209230 PRP4_HUMAN (51-253): 1.07e-12: 70.5: 25.85		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Dm
		1463899 WDS_DROME (5-253): 1.12e-72: 231: 18.82		WDS_DROME (174-342): 1.41e-22: 102: 10.53
+	Hs
		965141 WDR5_HUMAN (130-340): 4.37e-68: 218: 27.23		FBXW7_HUMAN (164-314): 4.21e-18: 92.2: 10.53
+	Hs
		209318 PRP4_HUMAN (51-253): 1.07e-12: 70.5: 25.85		SNR40_HUMAN (45-334): 1.8e-54: 196: 12.04
+	Hs
		845250 LIS1_HUMAN (259-340): 8.91e-19: 88.5: 23.17		LIS1_HUMAN (123-363): 2.02e-35: 142: 12.30
+	Mm
		988931 LIS1_MOUSE (259-340): 7.8e-19: 88.5: 23.17		LIS1_MOUSE (123-363): 1.82e-35: 142: 12.30
+	At
		200945 GBB_ARATH (132-340): 8.36e-39: 143: 23.32		GBLPA_ARATH (1-123): 2.81e-16: 83.7: 20.13
+	Hs
		1334151 POC1A_HUMAN (10-125): 2.55e-28: 115: 17.24		POC1B_HUMAN (1-83): 2.36e-16: 85.7: 16.28
+	Hs
		845346 LIS1_HUMAN (259-340): 8.91e-19: 88.5: 23.17		KTNB1_HUMAN (167-610): 4.74e-17: 88.7: 8.64