HitPredict

Interactor 1: ARHG6 (Q5ZLR6)
Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6)
Gene: ARHGEF6

Interactor 2: Q6LC82 (Q6LC82)
GTPase cRac1A
Gene: cRac1A

Species: Gallus gallus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	12686588
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~Ras, Ras~RhoGEF
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 764 Gg			1 192
+	Hs
		988376 ARHG6_HUMAN (1-763): 0: 584: 73.55		RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00
+	Hs
		581059 ARHG6_HUMAN (1-763): 0: 584: 73.55		RAC2_HUMAN (1-192): 2.74e-81: 241: 92.19
+	Hs
		1140198 ARHG6_HUMAN (1-763): 0: 584: 73.55		RHOJ_HUMAN (2-189): 1.39e-80: 240: 60.64
+	Hs
		953457 ARHG6_HUMAN (1-763): 0: 584: 73.55		RAC3_HUMAN (1-191): 3.71e-78: 233: 93.19
+	Hs
		955186 ARHG6_HUMAN (1-763): 0: 584: 73.55		CDC42_HUMAN (1-192): 5.32e-78: 232: 70.31
+	Hs
		601295 ARHG6_HUMAN (1-763): 0: 584: 73.55		RHOQ_HUMAN (4-190): 7.78e-73: 220: 63.16
+	Hs
		988358 ARHG7_HUMAN (1-707): 2.76e-162: 491: 54.86		RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00
+	Hs
		581039 ARHG7_HUMAN (1-707): 2.76e-162: 491: 54.86		RAC2_HUMAN (1-192): 2.74e-81: 241: 92.19
+	Hs
		1121983 ARHG7_HUMAN (1-707): 2.76e-162: 491: 54.86		RHOJ_HUMAN (2-189): 1.39e-80: 240: 60.64
+	Hs
		953440 ARHG7_HUMAN (1-707): 2.76e-162: 491: 54.86		RAC3_HUMAN (1-191): 3.71e-78: 233: 93.19
+	Hs
		955156 ARHG7_HUMAN (1-707): 2.76e-162: 491: 54.86		CDC42_HUMAN (1-192): 5.32e-78: 232: 70.31
+	Hs
		601284 ARHG7_HUMAN (1-707): 2.76e-162: 491: 54.86		RHOQ_HUMAN (4-190): 7.78e-73: 220: 63.16
+	Hs
		584511 VAV_HUMAN (1-742): 7.01e-128: 403: 18.23		RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00
+	Hs
		584504 VAV_HUMAN (1-742): 7.01e-128: 403: 18.23		CDC42_HUMAN (1-192): 5.32e-78: 232: 70.31
+	Hs
		913637 VAV2_HUMAN (1-734): 8.56e-121: 385: 16.18		RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00
+	Hs
		584505 VAV_HUMAN (1-742): 7.01e-128: 403: 18.23		RHOA_HUMAN (5-192): 1.33e-75: 226: 57.98
+	Hs
		913633 VAV2_HUMAN (1-734): 8.56e-121: 385: 16.18		CDC42_HUMAN (1-192): 5.32e-78: 232: 70.31
+	Hs
		988811 VAV3_HUMAN (1-739): 3.47e-112: 362: 17.00		RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00
+	Hs
		913634 VAV2_HUMAN (1-734): 8.56e-121: 385: 16.18		RHOA_HUMAN (5-192): 1.33e-75: 226: 57.98
+	Hs
		962621 VAV3_HUMAN (1-739): 3.47e-112: 362: 17.00		RHOA_HUMAN (5-192): 1.33e-75: 226: 57.98