Interactor 1: RAC1 (P63001)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)
Gene: RAC1
Interactor 2: CYFP1 (Q7TMB8)
Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1)
Gene: Cyfip1
Species: Mus musculus
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28671696 |
| Identification Methods | affinity chromatography technology, anti bait coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CYRIA-B_Rac1-bd~Ras, FragX_IP~Ras |
| Common GO terms | GO:0010592 - positive regulation of lamellipodium assembly GO:0016601 - Rac protein signal transduction GO:0030027 - lamellipodium GO:0030032 - lamellipodium assembly GO:0031529 - ruffle organization |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
