HitPredict

Interactor 1: RHOC (Q62159)
Rho-related GTP-binding protein RhoC (Silica-induced gene 61 protein) (SIG-61)
Gene: RHOC

Interactor 2: CYFP1 (Q7TMB8)
Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1)
Gene: Cyfip1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CYRIA-B_Rac1-bd~Ras, FragX_IP~Ras
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 193 Mm			1 1253
+	Mm
		988894 RAC1_MOUSE (1-193): 6.84e-81: 240: 57.22		CYFP1_MOUSE (1-1253): 0: 2088: 100.00
+	Hs
		962202 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		CYFP1_HUMAN (1-1253): 0: 2087: 99.04
+	Hs
		988476 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		CYFP1_HUMAN (1-1253): 0: 2087: 99.04
+	Hs
		1015548 RHOG_HUMAN (1-193): 2.26e-78: 233: 54.92		CYFP1_HUMAN (1-1253): 0: 2087: 99.04
+	Hs
		955323 CDC42_HUMAN (1-193): 8.86e-78: 232: 51.30		CYFP1_HUMAN (1-1253): 0: 2087: 99.04
+	Hs
		581134 RAC2_HUMAN (1-193): 2.92e-77: 231: 54.12		CYFP1_HUMAN (1-1253): 0: 2087: 99.04
+	Hs
		962370 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		CYFP2_HUMAN (1-1253): 0: 2075: 85.68
+	Hs
		988603 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		CYFP2_HUMAN (1-1253): 0: 2075: 85.68
+	Hs
		953525 RAC3_HUMAN (1-179): 7.81e-75: 225: 57.54		CYFP1_HUMAN (1-1253): 0: 2087: 99.04
+	Hs
		978112 RHOB_HUMAN (1-191): 6.1e-74: 222: 84.82		CYFP1_HUMAN (1-1253): 0: 2087: 99.04
+	Hs
		1015676 RHOG_HUMAN (1-193): 2.26e-78: 233: 54.92		CYFP2_HUMAN (1-1253): 0: 2075: 85.68
+	Hs
		581226 RAC2_HUMAN (1-193): 2.92e-77: 231: 54.12		CYFP2_HUMAN (1-1253): 0: 2075: 85.68
+	Hs
		953612 RAC3_HUMAN (1-179): 7.81e-75: 225: 57.54		CYFP2_HUMAN (1-1253): 0: 2075: 85.68
+	Dm
		828024 RAC1_DROME (1-193): 2.07e-78: 233: 54.12		CYFIP_DROME (1-1253): 0: 1909: 65.34
+	At
		1182489 RAC3_ARATH (2-193): 1.56e-92: 270: 48.99		PIR_ARATH (5-1240): 0: 1517: 28.66