HitPredict

Interactor 1: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Interactor 2: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008021 - synaptic vesicle GO:0030672 - synaptic vesicle membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 116 Hs			1 218
+	Hs
		907998 VAMP7_HUMAN (3-96): 2.55e-30: 109: 31.31		RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37
+	Hs
		1154622 VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78		RB11B_HUMAN (1-218): 6.92e-94: 275: 100.00
+	Hs
		1155382 VAMP8_HUMAN (20-99): 1.87e-24: 90.8: 32.50		RB11B_HUMAN (1-218): 6.92e-94: 275: 100.00
+	Hs
		278488 VAMP4_HUMAN (18-99): 3.79e-27: 98.9: 35.37		RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37
+	Hs
		192236 YKT6_HUMAN (5-85): 5.35e-25: 95.1: 24.69		RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37
+	Hs
		976192 VAMP2_HUMAN (25-116): 5.69e-26: 95.1: 100.00		RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37
+	Hs
		907995 VAMP7_HUMAN (3-96): 2.55e-30: 109: 31.31		RAB14_HUMAN (1-214): 1.09e-83: 249: 44.65
+	Hs
		908038 VAMP7_HUMAN (3-96): 2.55e-30: 109: 31.31		RAB2B_HUMAN (7-215): 1.34e-83: 249: 46.98
+	Hs
		976291 VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78		RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37
+	Hs
		981286 VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78		RAB1A_HUMAN (1-215): 5.62e-90: 264: 43.26
+	Hs
		976525 VAMP8_HUMAN (20-99): 1.87e-24: 90.8: 32.50		RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37
+	Hs
		1154737 VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78		RAB1B_HUMAN (4-215): 1.04e-86: 256: 44.81
+	Hs
		192226 YKT6_HUMAN (5-85): 5.35e-25: 95.1: 24.69		RAB25_HUMAN (2-218): 1.31e-83: 249: 60.63
+	Hs
		945004 VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78		RAB25_HUMAN (2-218): 1.31e-83: 249: 60.63
+	Hs
		957934 VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78		RAB14_HUMAN (1-214): 1.09e-83: 249: 44.65
+	Hs
		907994 VAMP7_HUMAN (3-96): 2.55e-30: 109: 31.31		RAB2A_HUMAN (8-178): 5.92e-61: 191: 55.56
+	Hs
		278486 VAMP4_HUMAN (18-99): 3.79e-27: 98.9: 35.37		RAB2A_HUMAN (8-178): 5.92e-61: 191: 55.56
+	Hs
		192231 YKT6_HUMAN (5-85): 5.35e-25: 95.1: 24.69		RAB2A_HUMAN (8-178): 5.92e-61: 191: 55.56
+	Hs
		956242 VAMP2_HUMAN (25-116): 5.69e-26: 95.1: 100.00		RAB2A_HUMAN (8-178): 5.92e-61: 191: 55.56
+	Hs
		956308 VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78		RAB2A_HUMAN (8-178): 5.92e-61: 191: 55.56