HitPredict

Interactor 1: THA (P63058)
Thyroid hormone receptor alpha (Nuclear receptor subfamily 1 group A member 1) (c-erbA-1) (c-erbA-alpha)
Gene: Thra

Interactor 2: Q8BK32 (Q8BK32)
Nuclear receptor co-repressor 1
Gene: Ncor1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.50	0.535

Property	Details
Experiments	21389087, 7566114
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 492 Mm			1 291
+	Hs
		278216 THA_HUMAN (1-492): 3.36e-156: 455: 95.73		NCOR1_HUMAN (1-290): 3.1e-132: 415: 92.07
+	Hs
		533313 THA_HUMAN (1-492): 3.36e-156: 455: 95.73		NCOR2_HUMAN (1-290): 1.66e-123: 390: 52.40
+	Hs
		278233 RXRA_HUMAN (3-408): 9.19e-115: 347: 24.09		NCOR1_HUMAN (1-290): 3.1e-132: 415: 92.07
+	Hs
		278203 ESR1_HUMAN (1-432): 2.73e-109: 338: 20.13		NCOR1_HUMAN (1-290): 3.1e-132: 415: 92.07
+	Hs
		278217 THB_HUMAN (22-407): 1.47e-107: 329: 71.24		NCOR1_HUMAN (1-290): 3.1e-132: 415: 92.07
+	Hs
		278263 HNF4A_HUMAN (1-411): 4.91e-107: 328: 22.82		NCOR1_HUMAN (1-290): 3.1e-132: 415: 92.07
+	Hs
		278285 NR1H2_HUMAN (2-407): 1.52e-105: 324: 23.85		NCOR1_HUMAN (1-290): 3.1e-132: 415: 92.07
+	Hs
		873173 RXRG_HUMAN (9-411): 4.03e-115: 349: 24.01		NCOR2_HUMAN (1-290): 1.66e-123: 390: 52.40
+	Hs
		278224 RARG_HUMAN (6-441): 3.28e-105: 323: 29.35		NCOR1_HUMAN (1-290): 3.1e-132: 415: 92.07
+	Hs
		625857 RXRA_HUMAN (3-408): 9.19e-115: 347: 24.09		NCOR2_HUMAN (1-290): 1.66e-123: 390: 52.40
+	Hs
		533238 RARB_HUMAN (5-441): 2.4e-113: 344: 30.37		NCOR2_HUMAN (1-290): 1.66e-123: 390: 52.40
+	Hs
		397334 ESR1_HUMAN (1-432): 2.73e-109: 338: 20.13		NCOR2_HUMAN (1-290): 1.66e-123: 390: 52.40
+	Hs
		1143714 Q15156_HUMAN (51-383): 3.87e-106: 335: 37.54		NCOR2_HUMAN (1-290): 1.66e-123: 390: 52.40
+	Hs
		533369 THB_HUMAN (22-407): 1.47e-107: 329: 71.24		NCOR2_HUMAN (1-290): 1.66e-123: 390: 52.40
+	Hs
		834104 HNF4A_HUMAN (1-411): 4.91e-107: 328: 22.82		NCOR2_HUMAN (1-290): 1.66e-123: 390: 52.40
+	Xl
		581937 THAA_XENLA (1-409): 1.85e-114: 345: 74.82		Q1W3Z6_XENLA (4-290): 1.93e-116: 370: 51.21
+	Xl
		581940 THAA_XENLA (1-409): 1.85e-114: 345: 74.82		NCOR1_XENLA (1-290): 2.66e-116: 369: 71.72
+	Mm
		789748 THB_MOUSE (22-407): 1.49e-107: 329: 70.47		Q8BK32_MOUSE (1-291): 4.75e-135: 385: 100.00
+	Hs
		933967 NR1H2_HUMAN (2-407): 1.52e-105: 324: 23.85		NCOR2_HUMAN (1-290): 1.66e-123: 390: 52.40
+	Xl
		612494 THBA_XENLA (35-407): 1.72e-114: 344: 75.60		NCOR1_XENLA (1-290): 2.66e-116: 369: 71.72