HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: CCNL2 (Q96S94)
Cyclin-L2 (Paneth cell-enhanced expression protein)
Gene: CCNL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	18216018
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck GO:0043484 - regulation of RNA splicing
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 520
+	Hs
		1028780 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		CCNL2_HUMAN (33-520): 1.65e-99: 311: 100.00
+	Hs
		1029048 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		CCNL2_HUMAN (33-520): 1.65e-99: 311: 100.00
+	Hs
		993807 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		CCNL2_HUMAN (33-520): 1.65e-99: 311: 100.00
+	Hs
		1028867 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		CCNL1_HUMAN (36-520): 1.19e-81: 265: 59.22
+	Hs
		1029152 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		CCNL1_HUMAN (36-520): 1.19e-81: 265: 59.22
+	Hs
		993865 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		CCNL1_HUMAN (36-520): 1.19e-81: 265: 59.22
+	Hs
		992986 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		CCNL1_HUMAN (36-520): 1.19e-81: 265: 59.22
+	Mm
		1161052 SRSF1_MOUSE (1-235): 1.04e-49: 165: 100.00		CCNT1_MOUSE (44-496): 1.42e-75: 254: 18.83
+	Hs
		952090 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		CCNL2_HUMAN (33-520): 1.65e-99: 311: 100.00
+	Hs
		1084377 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		CCNL2_HUMAN (33-520): 1.65e-99: 311: 100.00
+	Hs
		952173 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		CCNL1_HUMAN (36-520): 1.19e-81: 265: 59.22
+	Hs
		1084446 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		CCNL1_HUMAN (36-520): 1.19e-81: 265: 59.22
+	At
		1325350 PABP8_ARATH (5-159): 2.08e-25: 106: 14.65		CCB24_ARATH (23-316): 1.77e-77: 251: 14.53
+	At
		186467 PABP4_ARATH (5-246): 1.12e-24: 103: 13.53		CCH11_ARATH (64-353): 4.99e-53: 184: 16.89
+	Sc
		376841 PABP_YEAST (123-203): 2.42e-12: 68.1: 22.73		SSN8_YEAST (60-297): 1.58e-61: 206: 20.60