HitPredict

Interactor 1: ACTH (P63267)
Actin, gamma-enteric smooth muscle (EC 3.6.4.-) (Alpha-actin-3) (Gamma-2-actin) (Smooth muscle gamma-actin) [Cleaved into: Actin, gamma-enteric smooth muscle, intermediate form]
Gene: ACTG2

Interactor 2: CAP1 (Q01518)
Adenylyl cyclase-associated protein 1 (CAP 1)
Gene: CAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31839598
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~CAP_C, Actin~CAP_N
Common GO terms	GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 376 Hs			1 475
+	Hs
		1030734 ACTBL_HUMAN (1-376): 0: 713: 87.77		CAP1_HUMAN (1-475): 0: 711: 100.00
+	Hs
		818799 ACTBL_HUMAN (1-376): 0: 713: 87.77		CAP2_HUMAN (1-473): 0: 647: 63.05
+	Hs
		952753 ACTB_HUMAN (1-376): 0: 601: 93.35		CAP1_HUMAN (1-475): 0: 711: 100.00
+	Hs
		993137 ACTG_HUMAN (3-376): 0: 601: 94.39		CAP1_HUMAN (1-475): 0: 711: 100.00
+	Hs
		995545 ACTC_HUMAN (2-376): 0: 598: 98.67		CAP1_HUMAN (1-475): 0: 711: 100.00
+	Hs
		996429 ACTS_HUMAN (2-376): 0: 598: 98.13		CAP1_HUMAN (1-475): 0: 711: 100.00
+	Hs
		818783 ACTB_HUMAN (1-376): 0: 601: 93.35		CAP2_HUMAN (1-473): 0: 647: 63.05
+	Hs
		818787 ACTG_HUMAN (3-376): 0: 601: 94.39		CAP2_HUMAN (1-473): 0: 647: 63.05
+	Hs
		818795 Q1KLZ0_HUMAN (1-376): 0: 601: 93.35		CAP2_HUMAN (1-473): 0: 647: 63.05
+	Hs
		818788 ACTC_HUMAN (2-376): 0: 598: 98.67		CAP2_HUMAN (1-473): 0: 647: 63.05
+	Hs
		818789 ACTS_HUMAN (2-376): 0: 598: 98.13		CAP2_HUMAN (1-473): 0: 647: 63.05
+	Dm
		534434 ACT1_DROME (1-376): 0: 603: 94.15		Q7KN55_DROME (4-475): 0: 552: 42.89
+	Dm
		534492 ACT1_DROME (1-376): 0: 603: 94.15		Q9VPX7_DROME (43-475): 0: 552: 46.79
+	Dm
		387001 ACT2_DROME (1-376): 0: 602: 93.88		Q9VPX7_DROME (43-475): 0: 552: 46.79
+	Dm
		534380 ACT5_DROME (1-376): 0: 603: 92.82		Q9VPX6_DROME (4-475): 0: 530: 42.89
+	Dm
		534491 ACT1_DROME (1-376): 0: 603: 94.15		Q9VPX6_DROME (4-475): 0: 530: 42.89
+	Dm
		387000 ACT2_DROME (1-376): 0: 602: 93.88		Q9VPX6_DROME (4-475): 0: 530: 42.89
+	Dm
		921001 ACT3_DROME (1-376): 0: 601: 92.55		Q9VPX6_DROME (4-475): 0: 530: 42.89
+	Dm
		1014455 ACT6_DROME (1-376): 0: 600: 92.55		Q9VPX6_DROME (4-475): 0: 530: 42.89
+	Dm
		387071 ACT4_DROME (1-376): 0: 596: 92.29		Q9VPX6_DROME (4-475): 0: 530: 42.89