HitPredict

Interactor 1: PP2AA (P63330)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16)
Gene: Ppp2ca

Interactor 2: IGBP1 (Q61249)
Immunoglobulin-binding protein 1 (Alpha4 phosphoprotein) (CD79a-binding protein 1) (Lymphocyte signal transduction molecule alpha 4) (Protein phosphatase 2/4/6 regulatory subunit) (p52)
Gene: IGBP1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.800

Property	Details
Experiments	11371618, 19818709
Identification Methods	two hybrid, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Metallophos~TAP42
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 309 Mm			1 340
+	Hs
		994174 PP2AA_HUMAN (1-309): 0: 529: 99.68		IGBP1_HUMAN (3-340): 4.17e-128: 371: 80.47
+	Hs
		977458 PP2AB_HUMAN (1-309): 0: 527: 97.41		IGBP1_HUMAN (3-340): 4.17e-128: 371: 80.47
+	Mm
		977633 PP2AB_MOUSE (1-309): 0: 527: 97.41		IGBP1_MOUSE (1-340): 1.5e-127: 370: 100.00
+	Hs
		951961 PP4C_HUMAN (6-309): 0: 506: 65.25		IGBP1_HUMAN (3-340): 4.17e-128: 371: 80.47
+	Ce
		113999 PP2A_CAEEL (3-309): 0: 519: 89.25		PP4RS_CAEEL (1-340): 4.12e-98: 294: 29.86
+	Dm
		661973 PP2A_DROME (1-309): 0: 523: 93.85		Q9VJZ5_DROME (2-339): 1.14e-94: 287: 27.23
+	Dm
		304791 PP4C_DROME (8-309): 0: 519: 63.37		Q9VJZ5_DROME (2-339): 1.14e-94: 287: 27.23
+	Ce
		1445010 PP4C1_CAEEL (3-309): 0: 505: 62.46		PP4RS_CAEEL (1-340): 4.12e-98: 294: 29.86
+	Sc
		660880 PP2A2_YEAST (6-309): 0: 530: 75.66		TAP42_YEAST (43-340): 4.12e-76: 240: 23.26
+	At
		1058785 PP2A3_ARATH (7-309): 0: 511: 80.86		TAP46_ARATH (7-336): 8.21e-82: 255: 20.84
+	At
		1058776 PP2A2_ARATH (8-309): 0: 509: 79.80		TAP46_ARATH (7-336): 8.21e-82: 255: 20.84
+	At
		147070 PP2A5_ARATH (7-309): 0: 508: 80.20		TAP46_ARATH (7-336): 8.21e-82: 255: 20.84
+	At
		874361 PP2A4_ARATH (7-309): 0: 508: 80.86		TAP46_ARATH (7-336): 8.21e-82: 255: 20.84
+	At
		1058780 PP2A1_ARATH (8-309): 0: 504: 80.13		TAP46_ARATH (7-336): 8.21e-82: 255: 20.84
+	Sc
		660816 PP2A1_YEAST (6-309): 0: 517: 75.00		TAP42_YEAST (43-340): 4.12e-76: 240: 23.26
+	At
		873846 PPX1_ARATH (7-309): 5.85e-179: 497: 64.59		TAP46_ARATH (7-336): 8.21e-82: 255: 20.84
+	Sp
		661368 PP2A2_SCHPO (4-309): 0: 505: 78.76		YCJ5_SCHPO (8-340): 3.83e-62: 202: 26.78
+	Sp
		661357 PP2A1_SCHPO (7-309): 2.09e-179: 499: 79.54		YCJ5_SCHPO (8-340): 3.83e-62: 202: 26.78
+	At
		1319915 FYPP3_ARATH (9-309): 1.85e-135: 387: 57.62		TAP46_ARATH (7-336): 8.21e-82: 255: 20.84
+	Sc
		633509 PP11_YEAST (11-309): 1.5e-137: 393: 57.71		TAP42_YEAST (43-340): 4.12e-76: 240: 23.26