HitPredict

Interactor 1: ACTS (P68136)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: Acta1

Interactor 2: CNN1 (Q08290)
Calponin-1 (Basic calponin) (Calponin H1, smooth muscle)
Gene: CNN1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	17487264
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0015629 - actin cytoskeleton
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 377 Rn			1 297
+	Hs
		908656 ACTS_HUMAN (1-377): 0: 606: 100.00		CNN1_HUMAN (1-297): 8.19e-152: 428: 97.64
+	Hs
		995611 ACTC_HUMAN (1-377): 0: 606: 98.94		CNN3_HUMAN (4-287): 1.77e-136: 390: 70.63
+	Hs
		952837 ACTB_HUMAN (5-377): 0: 605: 93.83		CNN3_HUMAN (4-287): 1.77e-136: 390: 70.63
+	Hs
		995783 ACTC_HUMAN (1-377): 0: 606: 98.94		CNN2_HUMAN (1-290): 7.25e-133: 380: 61.07
+	Hs
		953052 ACTB_HUMAN (5-377): 0: 605: 93.83		CNN2_HUMAN (1-290): 7.25e-133: 380: 61.07
+	Dm
		387025 ACT4_DROME (1-377): 0: 651: 91.78		MP20_DROME (13-188): 1.05e-60: 192: 36.11
+	Dm
		387059 ACT4_DROME (1-377): 0: 651: 91.78		Q9I7J0_DROME (26-188): 2.56e-57: 183: 42.17
+	Hs
		790889 ACTC_HUMAN (1-377): 0: 606: 98.94		TAGL2_HUMAN (6-188): 3.94e-68: 212: 42.13
+	Hs
		790883 ACTB_HUMAN (5-377): 0: 605: 93.83		TAGL2_HUMAN (6-188): 3.94e-68: 212: 42.13
+	Hs
		790888 ACTG_HUMAN (4-377): 0: 605: 93.85		TAGL2_HUMAN (6-188): 3.94e-68: 212: 42.13
+	Dm
		920986 ACT3_DROME (1-377): 0: 602: 92.84		Q9I7J0_DROME (26-188): 2.56e-57: 183: 42.17
+	Sp
		153417 ACT_SCHPO (4-377): 0: 647: 89.04		IQG1_SCHPO (8-155): 1.08e-33: 132: 25.00
+	Hs
		862769 ACTB_HUMAN (5-377): 0: 605: 93.83		IQGA1_HUMAN (7-171): 1.48e-44: 163: 17.22
+	Hs
		862794 ACTG_HUMAN (4-377): 0: 605: 93.85		IQGA1_HUMAN (7-171): 1.48e-44: 163: 17.22
+	Hs
		952802 ACTB_HUMAN (5-377): 0: 605: 93.83		IQGA2_HUMAN (6-171): 5.61e-44: 162: 16.58
+	Hs
		953185 ACTB_HUMAN (5-377): 0: 605: 93.83		LIMC1_HUMAN (32-195): 1.57e-43: 160: 25.00
+	Hs
		996518 ACTS_HUMAN (1-377): 0: 606: 100.00		LRCH3_HUMAN (3-137): 1.82e-35: 137: 22.88
+	Hs
		995722 ACTC_HUMAN (1-377): 0: 606: 98.94		LMO7_HUMAN (38-143): 7.96e-28: 115: 29.75
+	Hs
		952987 ACTB_HUMAN (5-377): 0: 605: 93.83		LMO7_HUMAN (38-143): 7.96e-28: 115: 29.75